Breast cancer risk prediction model based on C5.0 algorithm for postmenopausal women

Xia Zhang, Yingming Sun
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引用次数: 1

Abstract

Breast cancer is one of the most common malignant tumors of women in the world, and it most happen in the elderly women, but in recent years the age of onset has become younger. As we know that, postmenopausal women are the groups with less research on breast cancer, and the characteristics of breast cancer are still to be explored. In this paper, based on the characteristic of 1031 postmenopausal women (⩾43 years old) breast cancer data, a breast cancer risk prediction model based on C5.0 algorithm was constructed and the model was optimized. The experimental results show that: a) Compared with machine learning methods such as neural network and support vector machine, C5.0 algorithm has better performance in constructing breast cancer risk prediction model; b) Costmatrix_C5.0 Model with cost matrix is better than adaptiveboosting_c5.0 model with Adaptive Enhancement algorithm; c) The risk of breast cancer is strongly correlated with post-menopausal hormones, age, age of menopause, history of benign breast disease and age of the first childbearing. This research is a practical application of data mining in the medical field and has certain reference value for the clinical diagnosis of breast cancer.
基于C5.0算法的绝经后妇女乳腺癌风险预测模型
乳腺癌是世界上最常见的女性恶性肿瘤之一,多发生于老年女性,但近年来发病年龄趋于年轻化。我们知道,绝经后妇女是乳腺癌研究较少的群体,乳腺癌的特点还有待探索。本文基于1031名绝经后妇女(大于或小于43岁)乳腺癌数据的特征,构建了基于C5.0算法的乳腺癌风险预测模型,并对模型进行了优化。实验结果表明:a)与神经网络、支持向量机等机器学习方法相比,C5.0算法在构建乳腺癌风险预测模型方面具有更好的性能;b)采用成本矩阵的Costmatrix_C5.0模型优于采用自适应增强算法的adaptiveboosting_c5.0模型;c)乳腺癌的风险与绝经后激素、年龄、绝经年龄、乳腺良性疾病史和首次生育年龄密切相关。本研究是数据挖掘在医学领域的实际应用,对乳腺癌的临床诊断具有一定的参考价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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