BETA-RADIATING RADIONUCLIDES FORMED IN A WATER TARGET OF A COMMERCIAL CYCLOTRON

Abstract

The accumulation of в-emitting radionuclides during irradiation of a liquid target of the Cyclone 18/9 HC commercial cyclotron and the production of radiopharmaceuticals (RP) based on 18F was studied by liquid scintillation spectroscopy. It is shown that with prolonged use of the target in the в-spectra of regenerated water [18O] H2O and ready-made RP [18F] NaF, in addition to the maximum due to tritium, a number of maxima appear in both the low-and high-energy parts of the spectrum. Storage for 3 months leads to a significant transformation of the spectra - the intensity of the low-energy wing of the regenerated water spectrum decreases sharply, the maximum in the 300 channel region disappears, while the intensity of the high-energy wing decreases not so dramatically. It was found that the tritium content in the regenerated water can be reliably estimated only after storage for 3 months.