Effect of Fermented Barley Fiber on Accumulation of Liver Lipids in Rats

Miki Umeki, Fumiko Ando, T. Iwahashi, Hideki Hokazono, Kei Hayashi, T. Omori, S. Mochizuki
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Abstract

We investigated that effects of fermented barley fiber (FBF) prepared from barley shochu lees, which was produced in manufacturing barley shochu, on lipid metabolism in rats. FBF contains about 50% of dietary fiber. The components of dietary fiber were hemicellulose, cellulose and lignin. Rats were fed on a relatively high-fat diet which contains 10% of lard, and 5% or 10% of FBF. FBF did not affect the levels of serum lipids. However, the concentrations of total lipids, triacylglycerol, and cholesterol in the liver were decreased by fed a FBF-containing diet. In another experiment, we fed a diet containing 20% of FBF with 1 % of orotic acid to rats. FBF prevented the accumulation of lipids in the liver and normalized the levels of serum lipids induced by orotic acid. From these results FBF was considered to possess the improvement effects on the accumulation of lipids in the liver.
发酵大麦纤维对大鼠肝脏脂质积累的影响
以大麦烧酒为原料,研究了发酵大麦纤维对大鼠脂质代谢的影响。FBF含有约50%的膳食纤维。膳食纤维的主要成分为半纤维素、纤维素和木质素。大鼠被喂食相对高脂肪的食物,其中含有10%的猪油和5%或10%的FBF。FBF对血脂水平无影响。然而,肝脏中总脂、甘油三酯和胆固醇的浓度在饲喂含fbf的饲料后有所降低。在另一个实验中,我们给大鼠喂食含有20% FBF和1%乳香酸的日粮。FBF可防止肝脏脂质积聚,使由山茱萸酸引起的血清脂质水平正常化。从这些结果来看,FBF被认为具有改善肝脏脂质积累的作用。
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