Implementation of new protocol for pain management following cardiac surgery

Z. Milan, Amy Rene Gomes, Mimi R. Borrelli, Mimi R. Borrelli, Gudran Kunst, K. Katyayni
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Abstract

Aims: We assessed the implementation and effectiveness of an updated protocol designed to improve pain management in cardiac surgery patients. The new updated protocol was recommended systemic pain assessment every four hours unless patients were unstable, using the numerical rating score (NRS) after the endotracheal extubation. Our secondary aim was to analyze the factors predicting patients’ postoperative pain to guide development of future pain management protocols. Methods: Fifty patients undergoing cardiac surgery with median sternotomy were evaluated in this audit. Perioperative details and details regarding analgesic administration were collected. High-risk patients were classified as ones with a history of substance misuse, chronic pain, and preoperative opioid use. Pain was measured at rest, on coughing and on moving, for the first three postoperative days (POD), using 11-point NRS (0–10). Pain was considered “unacceptable” if it was NRS ≥4 at rest, and NRS ≥8 on activity. A univariate and multivariate mixed model linear regression was used to investigate factors that may contribute to pain following cardiac surgery. Results: On POD1 38% of patients reported unacceptable pain at rest, and 27% reported unacceptable pain on coughing or moving. There was limited implementation of the new protocol, thus we cannot comment on the effectiveness of the updated protocol. Multivariate analysis demonstrated an overall significant interaction effect between postoperative day and risk (p = 0.032). It was found that high-risk patients reported pain to be greater than pain reported by low-risk patients on POD3 (2.14, CI −0.32 to 4.26, p = 0.054). Use of preoperative gabapentin did not affect pain at rest nor pain on coughing or moving (p > 0.5). Conclusion: The new pain protocol was not followed in the majority of patient cases. Preoperatively, only 25 (56%) patients received gabapentin. No patients received patient-controlled analgesia (PCA) postoperatively. Seven (15%) patients identified as high risk received no differential pharmacological management contrary to the updated protocol. It is believed that e-mail is not sufficient to implement a new protocol such as this, thus resulting in protocol implementation failure. However, it was found that postoperative pain differed between high-and low-risk patients, especially at rest. This indicates that risk assessment and individualized pain protocols are important to optimize postoperative pain management following cardiac surgery. We have discussed the efforts required to improve future protocol implementation and pain management across disciplines.
心脏手术后疼痛管理新方案的实施
目的:我们评估了一项旨在改善心脏手术患者疼痛管理的更新方案的实施和有效性。新的更新方案建议每4小时进行一次全身疼痛评估,除非患者不稳定,使用气管内拔管后的数值评分(NRS)。我们的第二个目的是分析预测患者术后疼痛的因素,以指导未来疼痛管理方案的发展。方法:对50例胸骨正中切开术心脏手术患者进行回顾性分析。收集围手术期细节和镇痛给药细节。高危患者分为有药物滥用史、慢性疼痛史和术前阿片类药物使用史的患者。术后前三天(POD),采用11点NRS(0-10)测量静息、咳嗽和活动时的疼痛。如果静止时NRS≥4,活动时NRS≥8,则认为疼痛“不可接受”。采用单因素和多因素混合模型线性回归研究可能导致心脏手术后疼痛的因素。结果:在POD1中,38%的患者在休息时报告不可接受的疼痛,27%的患者在咳嗽或移动时报告不可接受的疼痛。新议定书的实施有限,因此我们无法对更新后的议定书的有效性发表评论。多因素分析显示,术后天数与风险之间存在显著的交互作用(p = 0.032)。研究发现,在POD3上,高风险患者报告的疼痛大于低风险患者报告的疼痛(2.14,CI - 0.32 ~ 4.26, p = 0.054)。术前使用加巴喷丁对静息疼痛、咳嗽或移动疼痛无影响(p < 0.05)。结论:大多数患者未遵循新疼痛方案。术前,只有25例(56%)患者接受加巴喷丁治疗。无患者术后接受患者自控镇痛(PCA)。与更新后的方案相反,7例(15%)高风险患者未接受差异药理学治疗。人们认为电子邮件不足以实现这样的新协议,从而导致协议实现失败。然而,研究发现,高风险和低风险患者的术后疼痛有所不同,尤其是在休息时。这表明风险评估和个性化疼痛方案对于优化心脏手术后疼痛管理非常重要。我们讨论了改进未来协议实现和跨学科疼痛管理所需的努力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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