Preliminary Hazard Analysis (PHA): Great approach to risk analysis in pharmaceutical industry

Abstract

Preliminary Hazard Analysis (PHA) is a semi-quantitative evaluation executed to recognize, early within side the layout and definition level of a system, all potential hazards and hazardous events that can cause an accident, classify identified hazardous events according to their severity and identify the required hazard controls and their respective follow-up actions. It is a great tool for beginning to recognize the hazards of a system. In some cases, a PHA is all that is needed to analyse a simple system. It is also the first step in the hazard analysis of more complicated systems. This review illustrates PHA's use for analysing a maintenance process/procedure and discusses the injuries that can occur with poor design and recommend solutions.