[Subpopulation state of T and B lymphocytes in hemolytic-uremic syndrome in children].

Abstract

A study was made of the quantitative characteristics of T and B lymphocytes and of their subpopulations (A-RFC; E37-RFC; auto-RFC; EAC-RFC; Ig(+)-cells) as well as of 0-lymphocytes in the peripheral blood of 20 children aged 6 to 24 months with different clinical stages of the hemolytic-uremic syndrome (oligoanuria, diuresis onset, polyuria, clinical improvement). It is concluded that all the stages of the disease are characterized by the deficiency of certain subpopulations of T cells (especially A-RFC, E37-RFC), B lymphocytes, and 0-cells. By the moment of the clinical improvement, the cellular characteristics of the immune status do not return to normal.