Diana Carolina Carbajal-Lázaro, Andrew Emilio Castillo-Pacheco, Maujuri Jhojany Chigne-Abanto, Ángel Josué Delgado-Ramos, Leonardo Enrique Díaz-Layza, C. P. Escudero-Gaytán, Jorge Ulises Paredes-Landauro, Karla Luz del Rocío Casós-Portocarrero
{"title":"Psidium cattleianum as a possible treatment for oxidative stress caused by SARS-CoV-2 infection","authors":"Diana Carolina Carbajal-Lázaro, Andrew Emilio Castillo-Pacheco, Maujuri Jhojany Chigne-Abanto, Ángel Josué Delgado-Ramos, Leonardo Enrique Díaz-Layza, C. P. Escudero-Gaytán, Jorge Ulises Paredes-Landauro, Karla Luz del Rocío Casós-Portocarrero","doi":"10.17268/rmt.2022.v17i4.4647","DOIUrl":null,"url":null,"abstract":"The SARS-CoV-2 virus presents a lot of proteins in its structure that facilitate host cell infection, generating an increase in the concentration of angiotensin II and activating multiple signaling pathways that stimulate the NADPH oxidase enzyme complex and enzymes that take part in the inflammatory answer. As a consequence, there is an increase in reactive oxygen species (ROS) that damage different proteins, lipids and nucleic acids. Given this, Psidium cattleianumcan capture free radicals or inhibit theformation of ROS by transferring hydrogen atoms and electrons. For that, this research has the main objective to determine the influence of Psidium cattleianumas a possible treatment of oxidative stress caused by the SARS-COV-2 infection in order to consider the consumption of this berry as a possible alternative as an antioxidant treatment.","PeriodicalId":150228,"journal":{"name":"Revista Médica de Trujillo","volume":"42 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Médica de Trujillo","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17268/rmt.2022.v17i4.4647","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The SARS-CoV-2 virus presents a lot of proteins in its structure that facilitate host cell infection, generating an increase in the concentration of angiotensin II and activating multiple signaling pathways that stimulate the NADPH oxidase enzyme complex and enzymes that take part in the inflammatory answer. As a consequence, there is an increase in reactive oxygen species (ROS) that damage different proteins, lipids and nucleic acids. Given this, Psidium cattleianumcan capture free radicals or inhibit theformation of ROS by transferring hydrogen atoms and electrons. For that, this research has the main objective to determine the influence of Psidium cattleianumas a possible treatment of oxidative stress caused by the SARS-COV-2 infection in order to consider the consumption of this berry as a possible alternative as an antioxidant treatment.