Microscopic Image Analysis and Recognition On Pathological Cells

Boqiang Liu, Cong Yin, Zhongguo Liu, Zhenwang Zhang, Junbo Gao, Minghui Zhu, J. Gu, Kai Xu
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引用次数: 14

Abstract

According to the features of the configuration and color information on the cancer cells, an adaptive automatic threshold segmentation based on the RGB and HIS color spaces is presented, which is available to segment suspected cancer cells and nucleus from the complex backgrounds in the microscopic images. The edges of the suspected cancer cells and nucleus are detected by using Canny operator. Using the technology of eight-chain code tracking, the feature values of suspected cancer cells are extracted. The feature values consists of the perimeter, the area, the height, the width, the circularity, the rectangularity, the extension and the area ratio between the nucleus and the cytolympth. Based on feature values, a two-round recognition scheme combined with morphologic and colourometry is proposed to recognize and classify the pathological and normal cells. The results show that the proposed algorithm can efficiently segment cell images and receive higher accuracy of cancer cell diagnosis.
病理细胞的显微图像分析与识别
根据癌细胞的构型特征和颜色信息,提出了一种基于 RGB 和 HIS 色彩空间的自适应自动阈值分割方法,可将显微图像中的疑似癌细胞和细胞核从复杂的背景中分割出来。利用 Canny 算子检测可疑癌细胞和细胞核的边缘。利用八链码跟踪技术提取可疑癌细胞的特征值。特征值包括周长、面积、高度、宽度、圆形度、矩形度、延伸度以及细胞核与细胞膜的面积比。根据特征值,提出了一种结合形态学和色度学的双轮识别方案,对病理细胞和正常细胞进行识别和分类。结果表明,所提出的算法能有效地分割细胞图像,并获得更高的癌细胞诊断准确率。
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