ImmunoAdept – bringing blood microbiome profiling to the clinical practice

Abstract

Microbiome research aims to understand environmental features, relationships and microorganisms’ composition and their genomes. In the context of healthcare, microbiomics has unveiled that health status of the patient is more dependent on the microbiota than ever before thought. Here we present a pipeline designed to bring microbiome analysis to clinical practitioners in order to offer it as a service for diagnostic support. The Immunology Assay Development Platform (ImmunoAdept) enables the analysis of the whole-metagenome, therefore it can identify viruses, bacteria and archaea at species level. With the objective of making the ImmunoAdept platform broadly available, a cloud-based infrastructure was used, combined with an easy to use input and results interface. This was achieved by implementing it as part of Simplicity, TM a bespoke bioinformatics platform.