Multi-Modal Nanostructures for Measuring Ultra-Low Concentrations of Analytes in Complex Mediums

Abstract

Highly-sensitive lateral flow assay based on multi-modal nanostructures has been developed for detection of staphylococcal enterotoxin B in complex matrices. For optimization of assay parameters, kinetic characterization of immunoreagents, selection of immobilization interfaces and nanoparticles, modified label-free optical biosensors were used. The developed assay is rapid, easy-to-use, compatible with affordable consumables and different sample volumes, does not require sample pretreatment.