Taher M. Ghazal, Sagheer Abbas, Munir Ahmad, Shabib Aftab
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引用次数: 43
Abstract
Hepatitis C is considered a deadly disease as mortality rate in the patients suffering from this disease is very high, if not properly treated. This research proposes an IOMT based ensemble classification framework for the prediction of treatment response of a drug: “L-Ornithine-L-Aspartate” (LOLA) in hepatitis c patients. The treatment with this drug is called LOLA therapy which is significant for the patients to recover from the effects of hepatitis c disease. To implement the proposed framework, we used the medical data of hepatitis c patients who are being treated with LOLA therapy. The proposed framework integrates the predictive accuracy of two supervised machine learning techniques: Support Vector Machine (SVM) and Decision Tree (DT) by using Voting ensemble technique. The results reflect that the proposed ensemble framework performed well as compared to other published techniques on the prediction of treatment response for hepatitis c disease.
丙型肝炎被认为是一种致命的疾病,因为如果治疗不当,患有这种疾病的患者的死亡率非常高。本研究提出了一种基于IOMT的集成分类框架,用于预测丙型肝炎患者“l -鸟氨酸- l -天冬氨酸”(LOLA)药物的治疗反应。这种药物的治疗被称为LOLA疗法,对患者从丙型肝炎疾病的影响中恢复有重要意义。为了实施提议的框架,我们使用了正在接受LOLA治疗的丙型肝炎患者的医疗数据。该框架采用投票集成技术,将支持向量机(SVM)和决策树(DT)两种监督式机器学习技术的预测精度进行了集成。结果表明,与其他已发表的预测丙型肝炎治疗反应的技术相比,所提出的集成框架表现良好。