An Artificial Life Simulation to Observe DNA Sequence Repeat Pattern

Sabir Ismail, Mohaiminul Islam Bhuiyan, Shibbir Ahmad Osmani, M. A. Alim Mukul
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Abstract

This study presents an artificial life simulation to observe DNA sequence repeat pattern to observe probable repetitions of DNA sequence of an agent in future generations. This also includes research into recognizing patterns in repetitions and the ratio of unique and repetitive DNA sequences along with observing agent's evolution and life expectancy. We chose a small representative of life namely ‘agents'. The agents have sufficient intelligence to make survival decisions and can adapt to minor scenario changes. The 2D plane is optimized so that agents can move freely on the plane without clogging corners. The agents use diploid reproduction system and two-point crossover to produce offsprings. The agents also use simple learning algorithms and weighted random selection based movement logic. Simple logic that imitates Evolutionary processes further adapts the agents to their environment by making them more efficient. The DNA sequences are stored and activities of the agents of a population are monitored and logged accordingly in our system. After gathering data from successful sessions we analyze these data to observe patterns in repetitions of a previous DNA sequence and detect anomalies, observe life's evolving nature with time and the survival rate. The agents are evolved to ensure optimal ratio between unique and repetitive DNA sequences.
观察DNA序列重复模式的人工生命模拟
本研究提出了一种人工生命模拟方法来观察DNA序列重复模式,以观察一种病原体在后代中可能重复的DNA序列。这也包括识别重复模式的研究,以及独特和重复DNA序列的比例,以及观察代理的进化和预期寿命。我们选择了生命的一个小代表,即“代理人”。代理有足够的智能来做出生存决策,并能适应微小的场景变化。优化了二维平面,使agent可以在平面上自由移动,不会堵塞角落。利用二倍体生殖系统和两点杂交繁殖后代。智能体也使用简单的学习算法和基于加权随机选择的运动逻辑。模仿进化过程的简单逻辑进一步使代理更有效地适应其环境。DNA序列被储存起来,种群中的代理人的活动被监控并相应地记录在我们的系统中。在从成功的会话中收集数据后,我们分析这些数据以观察先前DNA序列的重复模式并检测异常,观察生命随时间和存活率的进化性质。这些试剂的进化是为了确保独特的和重复的DNA序列之间的最佳比例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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