[Characteristics of the effect of irradiation at different dose rates on survival, death kinetics and response of critical systems of the C57Bl/6 mice].

Abstract

A comparison was made of the biological effect on mice of irradiation at different dose rates (70, 5.5 and 1.5 cGy/min) with equally effective, with respect to lethality, doses, or with physically equal doses within the range from 1/4 of LD50/30 to LD99-95/30. Equally effective, with respect to lethality, doses caused similar changes in the intestinal epithelium and in the haemopoietic system. The death rate kinetics was identical with doses of LD80-95/30 within the dose-rate range under study. The equally effective doses caused injuries, different in degrees, to critical systems, including CFUs.