An Unlikely Telemedicine Diagnosis: A Case Report of Rhizobium Radiobacter Brain Abscess

Sridhi M. Patel, J. Cornely, Alejandro Isava, Hannah L. Winters, Anisha Mohandas, Amanda Costa
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Abstract

Introduction: Rhizobium radiobacter is a gram negative bacillus commonly found in soil The frequency ofreported infections in the pediatric population is rare and typically affects immunocompromised patients Thiscase highlights the incidence of a Rhizobium Radiobacter infection, prompted by a telemedicine consultation,in a healthy pediatric patient with no known risk factors Case Description: A 12-year-old male with a history ofchronic sinusitis and renal agenesis presented to the emergency department after a new-onset generalizedseizure The patient complained of having intermittent fevers for 5 days and left ear pain as well as left sidedperiorbital swelling He was febrile with elevated leukocytosis and inflammatory markers, and found to haveextensive left-sided sinusitis with no focal neurological deficits He was subsequently discharged withantibiotics and instructions to follow-up in one month with a pediatric neurologist Three days after the initialpresentation, he returned to the emergency department with persistent fever and headache He wasdetermined to have a sinus headache and instructed to complete the antibiotic course The following day, he was evaluated by pediatric neurology via telemedicine Secondary to the new onset seizures and changes inneurological status, he was referred for emergent inpatient admission Just prior to arrival, the patient had a20-minute nonverbal episode, prompting rapid video EEG placement which was suggestive of seizure activity The patient received a loading dose of levetiracetam and began maintenance dosing Despite AEDs, thepatient continued to have multiple subclinical seizures in the frontal lobe MRI brain was indicative ofmeningoencephalitis involving the left hemisphere, left frontal lobe cerebritis,and a multilocular extra-axialabscess At this time intravenous antibiotics were begun at meningitic dosing The patient was taken foremergent craniotomy for abscess evacuation, and cultures were found to be positive for RhizobiumRadiobacter Discussion: In the setting of fever and new-onset seizure in an otherwise healthy patient,meningitis should be high on the differential Infectious etiology cannot be excluded and necessitates furtherinvestigation including lumbar puncture with cerebrospinal fluid cultures The delay in ascertaining a spinaltap, alongside the late-onset of IV antibiotic use, propagated the formation of a bacterial abscess Conclusion:During the COVID-19 pandemic, the availability of telemedicine proved to be a lifesaving service The clinicalacumen of the neurologist prompted admission to the hospital for further evaluation and the eventualdiagnosis of a bacterial brain abscess A telehealth consultation with the patient in his home setting allowedfor the thorough history-taking required to develop the connection between the neurological changes andrecent sinusitis This case exemplifies the functionality of pediatric telemedicine and serves to highlight aunique pathogen in this patient population
不可能的远程医疗诊断:1例放射根瘤菌脑脓肿报告
放射根瘤菌是一种常见于土壤中的革兰氏阴性杆菌,在儿科人群中报道的感染频率很少见,通常影响免疫功能低下的患者。本病例突出了放射根瘤菌感染的发生率,由远程医疗咨询提示,在没有已知危险因素的健康儿科患者中。12岁男性,有慢性鼻窦炎和肾发育不全病史,新发全身性癫痫后就诊急诊。患者主诉间歇性发热5天,左耳疼痛,左侧眶周肿胀。发热伴白细胞和炎症标志物升高。他被发现患有广泛的左侧鼻窦炎,没有局灶性神经功能缺损,随后他被抗生素治疗出院,并被指示在一个月后与儿科神经科医生随访,在最初的表现三天后,他因持续发烧和头痛回到急诊科,他被确定为鼻窦头痛,并被指示在第二天完成抗生素疗程。继发于新发作的癫痫发作和神经系统状态的改变,他被转至紧急住院。就在到达之前,患者有20分钟的非语言发作,提示快速视频脑电图放置,提示癫痫活动。患者接受左乙拉西坦负荷剂量,并开始维持剂量,尽管有aed。患者继续在额叶出现多次亚临床癫痫发作,MRI提示脑膜脑炎累及左半球、左额叶脑炎和多房轴外水肿,此时开始以脑膜炎剂量静脉注射抗生素。患者接受合并开颅手术进行脓肿清除,发现放射根瘤菌培养阳性。在其他方面健康的患者出现发热和新发癫痫的情况下,脑膜炎的鉴别诊断应优先考虑,不能排除感染病因,需要进一步调查,包括腰椎穿刺和脑脊液培养。确定脊髓穿刺的延迟,加上静脉注射抗生素的延迟,促进了细菌性脓肿的形成。远程医疗的可用性被证明是一项挽救生命的服务。神经科医生的临床智慧促使他入院接受进一步的评估,并最终诊断为细菌性脑脓肿。在患者家中进行远程医疗会诊,可以进行全面的病史记录,以确定神经系统变化与近期鼻窦炎之间的联系在这个病人群体中有一种独特的病原体
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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