Study of role of autologous versus homologous cartilage ossicular reconstruction

Alpesh V. Patel, Payal R. Vadher, P. Patel, Vaishali N. Asodiya
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Abstract

Background: Chronic otitis media with ossicular discontinuity is most commonly faced otological condition which causes conductive hearing loss. It presents mostly with ear discharge and decreased hearing. The use of cartilage graft material in ossiculoplasty markedly improve the result in hearing. In this study we have used autologous (tragal/conchal) cartilage or homologous (septal) cartilage for ossiculoplasty and temporalis fascia graft for tympanoplasty.Aims: Aim of the study was to compare and analyze the outcome of ossiculoplasty using autologous conchal/tragal cartilage and homologous septal cartilage in terms of hearing results and graft uptake rates. Materials and method: The study was conducted in E.N.T. Department at S.C.L. Hospital, NHLMMC Ahmedabad. 50 patients were randomly selected and divided in 2 groups. 25 patients underwent homologous and 25 patients underwent autologous cartilage reconstruction. All patients underwent detailed ENT examination followed by audiological and radiological assessment of temporal bone, and those patients with evidence of ossicular erosion were subjected to ossiculoplasty with autologous cartilage and homologous cartilage randomly. Results: Majority of the patients have central perforation and retraction pockets in middle ear pathology in both groups. Overall graft taken up rate was 96% in autologous while 92% in homologous ossiculoplasty. Our study shows hearing improvement up to 20-25 dB in 80% and 88% in autologous and homologous ossiculoplasty. Conclusion: Both autologous and homologous cartilage have excellent outcomes and gives equivalent results irrespective of age or sex of the patient or middle ear pathology. In both the groups hearing improvement is similar. Subjective hearing is also improved. No post-op complications like wound infection, facial palsy, dead ear have occurred in either case.
自体与异体软骨听骨重建作用的研究
背景:慢性中耳炎伴听骨不连续是最常见的耳科疾病,可导致传导性听力损失。主要表现为耳部溢液和听力下降。在听骨成形术中使用软骨材料可以明显改善听力。在这项研究中,我们使用自体(耳门/耳廓)软骨或同源(中隔)软骨进行听骨成形术和颞筋膜移植进行鼓室成形术。目的:本研究的目的是比较和分析使用自体耳甲/耳甲软骨和同源鼻中隔软骨的听骨成形术在听力效果和移植物吸收率方面的结果。材料与方法:研究在印度艾哈迈达巴德医院s.c.l医院耳鼻喉科进行,随机选取50例患者分为两组。25例患者行同种软骨重建,25例患者行自体软骨重建。所有患者均行详细的耳鼻喉科检查,并对颞骨进行听力学和影像学检查,对有听骨侵蚀证据的患者随机行自体软骨和同源软骨听骨成形术。结果:两组患者病理均以中耳中央性穿孔和后缩袋为主。自体骨成形术整体移植率为96%,同种骨成形术整体移植率为92%。我们的研究表明,自体和同源听骨成形术的听力改善高达80%至25db, 88%。结论:不论患者的年龄、性别或中耳病理,自体和异体软骨均有良好的疗效。两组的听力改善情况相似。主观听力也有所提高。两例术后均无伤口感染、面瘫、死耳等并发症发生。
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