Coexistence of Genital and Extragenital LSA with Dermoscopic Features

Krati Mehrotra, Molisha Bhandari, Shruti Sharma, Niti Khunger
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Abstract

Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory dermatosis, primarily involving the anogenital region, and sometimes extragenital sites (15–20%). Rarely, patients can present with only extragenital lesions (2.5%). A 50-year-old female presented with depigmented lesions on vulva, bilateral knees and legs for 1½ years. Dermoscopy showed patchy white structureless areas with follicular plugs and histopathological examination revealed focal vacuolar degeneration of the basal layer and hyalinisation in the papillary dermis, with mild perivascular lymphohistiocytic inflammation, helping confirm the diagnosis of genital and extragenital LSA. Thus, the authors elaborate the rarity of coexistence of genital and extragenital LSA in a single patient and the use of dermoscopy as a tool in its diagnosis.
生殖器和生殖器外LSA与皮肤镜特征共存
硬化性萎缩性地衣(LSA)是一种慢性炎症性皮肤病,主要累及肛门生殖器区域,有时累及生殖器外部位(15-20%)。极少数情况下,患者仅表现为生殖器外病变(2.5%)。一位50岁的女性,因外阴、双膝和腿上的色素脱色病变而住院1年半。皮肤镜检查显示斑片状白色无结构区伴滤泡塞,组织病理学检查显示基底层局灶性空泡变性和乳头状真皮透明化,伴轻度血管周围淋巴组织细胞炎症,有助于确认生殖器和生殖器外LSA的诊断。因此,作者详细阐述了罕见的共存生殖器和外生殖器LSA在一个病人和使用皮肤镜作为其诊断的工具。
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