Appraisal of an Innovative Surgical Approach in treating Odontogenic Keratocyst

Ananya Bej, Sthitaprajna Lenka, R. Nagarajappa, S. Sahoo, S. Subudhi, Karishma Rathore, Aditi Ava Rath
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Abstract

To estimate the recurrence of odontogenic keratocyst (OKCs) and increment of bone height upon an innovative treatment protocol of the OKC, i.e., enucleation along with the adjuvant therapy of Carnoy’s solution, followed by marsupialization. Twenty cases of OKC treated at the Department of Oral and Maxillofacial Surgery from 2020-2021 were studied retrospectively. Clinical, radiological features and histologic features were reviewed. The patients diagnosed with OKCs were planned for enucleation with the use of Carnoy's solution and followed by marsupialization. Recurrence of the same and bone formation was analyzed concerning sites of involvement, based upon the gender and age group of patients, after undergoing the proposed treatment. Mean age of the patients was 35.15±13.02, ranging from 11 to 56 years. Most (85%) patients were symptomatic, and the remaining (15%) were asymptomatic and diagnosed on a routine check-up. Males (65%) were mostly affected than females (35%). Mandible (75%) was the most frequent site of occurrence. Most lesions were diagnosed histologically as OKC on incisional biopsy. All patients were followed for six months, an increment of 11.11±1.68mm bone height was seen, and none reported recurrence. The steady growth of bone without any cases of recurrence was reported. Hence, clinicians can consider enucleation along with adjuvant therapy using Carnoy's solution followed by marsupialization as the treatment of choice.
一种治疗牙源性角化囊肿的创新手术方法的评价
评估牙源性角化囊肿(OKCs)的复发和骨高的增加,在OKCs的创新治疗方案,即去核与Carnoy的溶液辅助治疗,然后有袋化。对2020-2021年口腔颌面外科收治的20例OKC进行回顾性研究。复习临床、影像学及组织学特征。诊断为OKCs的患者计划使用Carnoy's溶液进行去核,然后进行有袋化。根据患者的性别和年龄组,在接受拟议的治疗后,分析了相同的复发和骨形成有关受累部位。患者平均年龄35.15±13.02岁,年龄11 ~ 56岁。大多数(85%)患者有症状,其余(15%)无症状,在常规检查中被诊断出来。受影响最大的是男性(65%),而不是女性(35%)。下颌(75%)是最常见的发生部位。大多数病变在切口活检组织学上被诊断为OKC。随访6个月,骨高增加11.11±1.68mm,无复发。骨生长稳定,无复发病例。因此,临床医生可以考虑使用Carnoy溶液进行辅助治疗,然后将有袋化作为治疗选择。
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