Imaging of dendrites and sparse interneuronal networks with 3D random access microscopy

Abstract

Acousto-optical microscopy is a powerful tool to study spare networks and extensive dendritic arborization from the cortex of behaving animals. We used this novel approach for imaging dendrites and somata of sparse interneuron populations in a combination with auditory discrimination and detection tasks. Our results shed light of not yet known subcellular and network mechanisms from multiple brain regions.