FATORES DE RISCO E SOROPREVALÊNCIA DE ASSINTOMÁTICOS DA LEISHMANIOSE VISCERAL HUMANA EM ÁREA DE TRANSMISSÃO INTENSA EM PETROLINA/PE, BRASIL

Abstract

OBJECTIVES: To identify the seroprevalence of asymptomatic individuals in areas of disease transmission and analyze the environmental, socioeconomic and demographic risk factors in the municipality of Petrolina/PE, Brazil. METHODS: We approached 92 individuals in 19 localities with VL cases recorded in the Information System for Notifiable Diseases (SINAN) between 2016 and 2017. In each visit, two questionnaires were applied seeking to obtain clinical, social, economic and environmental variables. Viable blood samples collected during the visits (n=90) were submitted to the Indirect Immunofluorescence Reaction to identify anti-Leishmania antibodies. For data analysis, descriptive statistical tests were performed using Stata® 14.0 software. RESULTS: The presence of antibodies was detected in 2.2% (2/90) of the samples, in which one individual presented symptoms and the other was classified as asymptomatic. No risk factors related to the presence of anti-Leishmania antibodies were identified. CONCLUSION: The identification of one asymptomatic individual reinforces the importance of expanding human prevalence studies in endemic areas. Despite the low prevalence, it was possible to identify a possible case with manifestation of the clinical form of chronic VL that needs proper care.