Probiotics Intervention in Woman Health: Unexpected Acquaintance

K. Naidu
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Abstract

There is growing interest in health promoting benefits of probiotics as bio therapeutic agents. Probioticsare used to treat recurrent urinary tract infections, diabetes, diarrhoea, vulvovaginal candidiasis and bacterial vaginosis in women. Probiotics exert their positive effects through various mechanisms, including lowering intestinal pH, decreasing colonization and invasion by pathogenic organisms, and modifying the host immune response. There is no agreement about the minimum number of microorganisms that must be consumed to obtain a beneficial effect; however, a probiotic should typically contain several billion microorganisms to increase the chance that adequate gut colonization will occur. This review presents mechanisms of action of probiotics and briefly examines the recent developments in use of probiotics in treating both infectious and non-infectious diseases in relation to women’s health. We conclude with suggestions for future work and possible applications probiotic research.
益生菌干预妇女健康:意想不到的认识
人们对益生菌作为生物治疗剂的健康促进作用越来越感兴趣。益生菌用于治疗女性复发性尿路感染、糖尿病、腹泻、外阴阴道念珠菌病和细菌性阴道病。益生菌通过多种机制发挥其积极作用,包括降低肠道pH值、减少病原菌的定植和侵袭、调节宿主免疫反应等。对于必须消耗多少微生物才能获得有益效果,目前还没有达成一致意见;然而,益生菌通常应该包含数十亿微生物,以增加肠道定植的机会。本文综述了益生菌的作用机制,并简要介绍了益生菌在治疗与妇女健康有关的感染性和非感染性疾病方面的最新进展。最后,对今后的工作和应用前景提出了建议。
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