PALLIATIVE SURGICAL TREATMENT OF UNRESECTABLE TUMORS OF THE HEAD OF THE PANCREAS COMPLICATED BY MECHANICAL JAUNDICE AND DUODENAL OBSTRUCTION BY STENTING OF THE BILIARY SYSTEM AND DUODENUM WITH NITINOL STENTS

B. Bezrodnyi, I. Kolosovich, V. P. Slobodjanyk, O. M. Petrenko, M. Filatov
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Abstract

Summary. The development of new technological solutions for palliative surgical treatment of patients with unresectable pancreatic cancer is relevant because the frequency of postoperative complications in such patients reaches 25 % and mortality — 20 %. Objective. Improve the diagnosis and immediate results of palliative surgical treatment of patients with unresectable pancreatic cancer complicated by mechanical jaundice and duodenal obstruction. Materials and methods. A comparative analysis of the results of surgical treatment of two groups of patients (11 patients in the first and 27 in the second) for unresectable pancreatic cancer complicated by mechanical jaundice and gastric evacuation disorders due to duodenal obstruction. Patients of group I performed only biliodigestive shunting by open surgery. Patients in group II obstruction of the bile ducts and duodenum was removed by endoscopic stenting of the biliary system and duodenum with nitinol stents. Results. It is proved that endoscopic stenting of the biliary system and duodenal obstruction by nitinol stents, compared with open surgery, is accompanied by a lower frequency of postoperative complications (72.7 % vs. 22.2 %, p < 0.05), mortality (27.3 % vs. 0 %, p < 0.001) and reduction of hospital stay (from (24.3 ± 3.74) to (8.7 ± 0.91) days, p <0.001). Conclusions. The operation of choice of palliative surgical treatment of patients with unresectable pancreatic cancer complicated by mechanical jaundice and evacuation disorders from the stomach, with a high risk of surgery (ASA III), is to perform endoscopic transpapillary stenting of the bile ducts and duodenum.
应用镍钛诺支架置入术治疗无法切除的胰头肿瘤合并机械性黄疸及十二指肠梗阻的姑息性手术
总结。对于无法切除的胰腺癌患者的姑息性手术治疗的新技术解决方案的发展是相关的,因为这类患者的术后并发症发生率达到25%,死亡率达到20%。目标。提高不可切除胰腺癌合并机械性黄疸及十二指肠梗阻患者姑息性手术治疗的诊断及即时效果。材料和方法。比较分析两组不可切除胰腺癌合并机械性黄疸及十二指肠梗阻所致胃排液障碍的手术治疗结果(第一组11例,第二组27例)。I组患者仅行开放手术胆道消化分流术。II组胆管及十二指肠梗阻患者行内镜下胆道及十二指肠支架置入术。结果。结果表明,与开放手术相比,内镜下胆道系统和十二指肠梗阻支架置入术术后并发症发生率(72.7% vs. 22.2%, p < 0.05)、死亡率(27.3% vs. 0%, p <0.001)和住院时间(从(24.3±3.74)天减少到(8.7±0.91)天,p <0.001)较开放手术低。结论。不可切除的胰腺癌合并机械性黄疸和胃排空障碍,手术风险高(ASA III),姑息性手术治疗的选择是内镜下胆管和十二指肠经毛细血管支架置入术。
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