The Effects of Recove Ointment on Wound Healing in Mothers Susceptible to Cesarean Section Infection

P. Yekta, Main Tafazolim, H. Rakhshandeh, H. Esmaeili, Masoumeh Mirtaymori
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Abstract

Background & aim: Due to the development of major complications after cesarean section (C-section), surgical site infection and delayed wound healing was of great concern to gynecologists since a long time ago. It is especially the case for mothers susceptible to post-cesarean wound infection who need special care. The present study therefore aimed to investigate the effect of Recove ointment on wound healing in women susceptible to C-section wound infection. Methods: In this triple-blind randomized clinical trial, which was conducted on the women who underwent C-section in Ommolbanin Hospital, Mashhad, in 2019, using a two-group design, a number of 80  eligible women with C-section were assigned into intervention and placebo groups. Intervention group received Recove ointment for a maximum of 10 days. The wound recovery was assessed using Reeda scale before intervention and 3, 5, and 10 days after C-section. Data were analyzed using T test and Mann-Whitey, Chi-square as well as Fisher's exact test. Results: The score of wound healing was significantly different in intervention and control group 5 days after cesarean section (P=0.008). But no significant difference was seen between two groups on days 3 and 10 post cesarean (P=0.69). Also there was significant difference between wound healing score before and after intervention in both intervention (P=0.001) and placebo groups (P=0.001). Conclusion: Although the effectiveness of the ingredients of Recove ointment was indicated in several studies, this ointment was revealed to be effective for wounds healing just 5 days after cesarean section. Further research with larger sample size is required to investigate the effect of this ointment.
恢复软膏对剖宫产感染易感产妇创面愈合的影响
背景与目的:由于剖宫产术后主要并发症的发展,手术部位感染和伤口愈合延迟一直是妇科医生关注的问题。对于易受剖宫产后伤口感染、需要特殊护理的母亲尤其如此。因此,本研究旨在探讨Recove软膏对易受剖腹产伤口感染的妇女伤口愈合的影响。方法:对2019年在马什哈德Ommolbanin医院剖腹产的妇女进行三盲随机临床试验,采用两组设计,将80名符合条件的剖腹产妇女分为干预组和安慰剂组。干预组给予康复软膏治疗,疗程最长为10天。干预前及剖腹产后3、5、10 d采用Reeda评分法评估创面恢复情况。数据分析采用T检验、Mann-Whitey检验、卡方检验和Fisher精确检验。结果:干预组与对照组剖宫产术后5 d创面愈合评分差异有统计学意义(P=0.008)。剖宫产后第3、10天两组间差异无统计学意义(P=0.69)。干预前后创面愈合评分与安慰剂组比较差异均有统计学意义(P=0.001)。结论:虽然多项研究表明Recove软膏成分的有效性,但该软膏对剖宫产术后仅5天的伤口愈合有效。进一步的研究需要更大的样本量来调查这种软膏的效果。
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CiteScore
1.10
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