Medical Use of Povidone Iodine Against Covid-19. Why Not?

Abstract

Povidone-iodine (PVP-I) is an old antiseptic used in practice of medicine as a surgical scrub; for preand post-operative skin cleansing; for the treatment and prevention of infections in wounds, decubitus ulcers, cuts, and burns; in gynecology for vaginitis associated with candidal, trichomonal or mixed infections. For these purposes, PVP-I has been formulated at concentrations of 7.510.0% in solution, nasal and throat spray, surgical scrub, ointment, swab dosage forms, eye drop, and vaginal suppositories. The safety profile of PVP-I at such concentrations is well established and many available products in the market are over the counter. The most well-known brand for PVP-I is BETADINE.