Choriocarcinoma in Cesarean Scar Site: A Case Report

H. Azimi, L. Shirinzadeh, A. Jafarian, Behroz Davachi, S. Bolandi, S. Hoseini, Tahereh Zavvari, Z. Yousefi, Fatemeh Shirzadeh
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Abstract

Background & aim: Cesarean scar pregnancy is an ectopic pregnancy implanted in the myometrium at the site of a previous cesarean section scar and is the rarest kind of ectopic pregnancy. The present study present a case of choriocarcinoma (CC) in the cesarean scar. The clinical course, findings, and treatment plan are discussed. Case report: A 41-years old multi-gravid woman with a history of one previous cesarean section and three subsequent abortions was admitted to the hospital. She suffered from an unknown abnormal vaginal bleeding for two months. Β-HCG titer was 1,000 IU/L and the report of sonography showed no gestational sac. Accordingly, the patient was diagnosed with ectopic pregnancy in the cesarean scar site and, therefore, weekly usage of methotrexate was prescribed for her. Since she did not respond to the treatment, she was referred to our department in the Faculty of Medicine. The evaluation showed mass invasion through the entire uterine wall. The uterus preservation was not possible, therefore, total hysterectomy was performed. The pathology report confirmed CC in the cesarean scar. Conclusion: Based on previous studies, as the number of cesarean sections increases, the possibility of complications rises, as well.  Cesarean scars implantation of CC is one of the rare complications of caesarean section. The probability of a gestational trophoblastic disease should be considered in any woman during her pregnancy. Early detection and proper management of the complications can result in a decrease in morbidity and mortality.
剖宫产瘢痕部位绒毛膜癌1例报告
背景与目的:剖宫产瘢痕妊娠是一种在剖宫产瘢痕部位植入子宫肌层的异位妊娠,是最罕见的一种异位妊娠。本文报告一例剖宫产瘢痕的绒毛膜癌(CC)。讨论了临床过程、结果和治疗方案。病例报告:一名41岁多孕妇女,既往有一次剖宫产史,随后有三次流产。她遭受了两个月不寻常的阴道出血。Β-HCG滴度为1000 IU/L,超声检查未见妊娠囊。因此,患者被诊断为剖宫产疤痕部位异位妊娠,因此,每周使用甲氨蝶呤。由于治疗无效,她被转介到我们医学院的科室。检查显示肿块侵入整个子宫壁。由于无法保留子宫,故行全子宫切除术。病理报告证实剖宫产瘢痕为CC。结论:根据以往的研究,随着剖宫产手术数量的增加,并发症的可能性也随之增加。剖宫产瘢痕植入术是剖宫产术中一种罕见的并发症。任何妇女在怀孕期间都应考虑妊娠滋养细胞疾病的可能性。早期发现和适当处理并发症可降低发病率和死亡率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
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