Comparison of Pregnant and Non-pregnant Women With COVID-19 Infection

T. F. Hernandez, Richard Alexander Sera Blanco, Teresa Sandra Erice Rivero, Oreste Mojena Mojena, R. R. Jimenez, D. Concepción
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引用次数: 1

Abstract

Background: Covid-19 infected pregnant women has been reported worst outcome than non-pregnant due to physiological and immunological changes mainly in the third trimester of pregnancy. Methods: Observational analytic retrospective study with Covid-19 infected 411 women, whose ranges of age were between 18 to 52 years old divided in two groups; 84 pregnant and 327 non-pregnant admitted in The Cuban Hospital of Qatar, since April 1st to June 30th of 2020. It was aimed to compare both groups according to clinical, laboratory, radiological and main outcomes. Analysis of frequencies, Ji Square, Variance and Odds Ratio were performed. Results: Pregnant tended to be younger and predominated third trimester of pregnancy; obesity, vitamin D deficiency and asymptomatic infection prevailed in pregnant and were significant. Fever and cough were more frequent in non-pregnant. Chest X ray showed Focal Bilateral lesions prevailed in non-pregnant; most of pregnant did not do X rays. D- dimer and alkaline phosphatase were higher in pregnant, alanine amine transferase was higher in non-pregnant. 4 to 7 days of hospital stay predominated in pregnant. Oxygen therapy, moderate and severe respiratory distress and intensive care unit admission were predominant in pregnant. No lethality was observed in pregnant with Covid-19 infection. Conclusion: Covid-19 pregnant are younger and has higher probability of asymptomatic disease; but they have higher risk of co-morbidities, respiratory failure, intensive care admission and mechanical ventilation; mortality risk is higher in non-pregnant.
孕妇与非孕妇COVID-19感染的比较
背景:据报道,由于主要在妊娠晚期发生的生理和免疫变化,感染Covid-19的孕妇预后比未怀孕的孕妇最差。方法:观察性分析回顾性研究新冠肺炎感染妇女411例,年龄18 ~ 52岁,分为两组;自2020年4月1日至6月30日,84名孕妇和327名非孕妇在卡塔尔古巴医院入院。目的是根据临床、实验室、放射学和主要结果对两组进行比较。进行频率分析、吉方分析、方差分析和比值比分析。结果:妊娠倾向年轻化,以妊娠晚期为主;肥胖、维生素D缺乏和无症状感染在孕妇中普遍存在,且具有显著性。发热和咳嗽在非孕妇中更为常见。胸部X线显示:未怀孕者以局灶性双侧病变为主;大多数孕妇不做X光检查。孕妇D-二聚体和碱性磷酸酶较高,非孕妇丙氨酸胺转移酶较高。妊娠期以住院4 ~ 7天为主。孕妇以氧疗、中重度呼吸窘迫和重症监护病房住院为主。感染新冠病毒的孕妇未见死亡。结论:新冠肺炎孕妇年龄小,无症状发病概率高;但他们的合并症、呼吸衰竭、重症监护入院和机械通气的风险较高;非孕妇的死亡率更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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