Ion Partition Detected in Homeopathically Manufactured Medicine Cuprum metallicum and Controls

M. Wassenhoven, B. Nysten, Martine Goyens, P. Dorfman, P. Devos, D. Magnin
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Abstract

Background: Homeopathy is highly controversial. The main reason for this is its use of very highly dilute medicines (high homeopathic potencies, HHP), diluted beyond the Avogadro/Loschmidt limit. Research using Nano Tracking Analysis has demonstrated the presence of particles in HHPs. This study aims to verify the results of a previous publication that identified the ionic composition of these particles in all dilutions. Methods: We used Scanning Electron Microscopy & Energy Dispersive X-Ray Spectroscopy (SEM-EDX) to examine dilutions of a commonly used homeopathic medicine, an insoluble metal, Cuprum metallicum, for the presence of particles (NPs). The homeopathic medicines tested were specially prepared according to the European pharmacopoeia standards. We compared the homeopathic dilutions/dynamizations of copper with simple dilutions and dynamized lactose controls. Results: We observed an ionic diversity common to all preparations including HHPs but also significant differences in the relative quantity of each ion between manufacturing lines of homeopathic copper and lactose controls. The probability that the observed differences could have occurred chance alone (especially above Avogadro limit) can be rejected at p < 0.001. The essential component of these homeopathic medicines is sodium hydrogen carbonate, modulated by some other elements and by its quantity, size and shape. Conclusion: Homeopathic medicines made of Cuprum metallicum do contain material with a specific ionic composition even in HHPs diluted beyond the Avogadro/Loschmidt limit. This specificity can be attributed to the manufacturing process. This material demonstrates that the step-by-step process (dynamized or not) does not match the theoretical expectations of a dilution process. The starting material and dilution/dynamization method influences the nature of these NPs. Further measurements are needed on other raw materials using the same controls (solvent and simply diluted manufacturing lines) to support these findings. The role of sodium bicarbonate must be carefully studied in the future.
顺势疗法药物金属铜离子分割检测及对照
背景:顺势疗法备受争议。其主要原因是它使用了非常稀释的药物(高顺势疗法效力,HHP),稀释超过阿伏伽德罗/洛施密特极限。使用纳米跟踪分析的研究已经证明了HHPs中存在颗粒。本研究旨在验证先前发表的结果,该结果确定了这些颗粒在所有稀释下的离子组成。方法:我们使用扫描电子显微镜和能量色散x射线光谱学(SEM-EDX)来检查一种常用的顺势疗法药物,一种不溶性金属,金属铜,是否存在颗粒(NPs)。所测试的顺势疗法药物是根据欧洲药典标准专门配制的。我们比较了顺势疗法稀释/动态铜与简单稀释和动态乳糖对照。结果:我们观察到包括HHPs在内的所有制剂的离子多样性,但顺势疗法铜和乳糖对照的生产线之间每种离子的相对数量也有显著差异。可以在p < 0.001时拒绝观察到的差异可能单独发生的概率(特别是高于阿伏伽德罗极限)。这些顺势疗法药物的基本成分是碳酸氢钠,由一些其他元素及其数量、大小和形状调节。结论:由金属铜制成的顺势疗法药物,即使在稀释超过阿伏伽德罗/洛施密特极限的HHPs中,也含有具有特定离子组成的物质。这种特异性可归因于制造工艺。该材料表明,一步一步的过程(动态或非)不符合稀释过程的理论期望。起始材料和稀释/动力化方法影响这些NPs的性质。需要使用相同的控制(溶剂和简单稀释的生产线)对其他原材料进行进一步的测量来支持这些发现。今后必须仔细研究碳酸氢钠的作用。
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