Visceral Adiposity Index in Type 2 Diabetes Mellitus and Its Risk for Cardiovascular Disease

K. H. Parveen, F. H. Mollah, T. Parvin, A. A. Khan, P. K. Datta, Toufiq Ahmed, Nondita Mudi, Mahdeen Ahmed Khan Sameer, M. Arslan
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Abstract

Back ground: The Visceral Adiposity Index (VAI) is an empirical mathematical model, genderspecific, based on simple anthropometric (BMI and WC) and functional parameters (triglycerides (TG) and HDL cholesterol (HDL)), and indicative of fat distribution and function. Methods: This is a Cross sectional study. It was carried out in the department of Biochemistry, BSMMU from July 2015- June 2017. Type 2 Diabetes Mellitus patients attending in outpatient Department of Endocrinology and Metabolism, BSMMU were our study population. The cutoff value for VAI was considered as 3. Results: We enrolled 105 participants in this study. Among them 41 were male and 64 were female. There was significant difference between male and female in terms of height, weight and BMI. Male had greater height (p =0.01) and weight (p =0.01) than female. Female had greater BMI (p =0.01) than male. The majority of male and female scored above the cut off value of VAI which were 63.4% and 59.4% respectively. The mean value of biochemical parameters TG, FBG and HbA1c were significantly different on the basis of cutoff point of VAI (d”3 and > 3). There is increased TG, FBG and HbA1c and decreased HDL-C with the cut off value more than 3 in VAI. We found significant strong positive correlation with HbA1c with FRS (r= +.631, p=<0.001) and VAI (r= +.596, p=<0.001) Conclusion: High Visceral Adiposity Index is associated with Type 2 diabetes mellitus and increased cardiovascular risk J Dhaka Med Coll. 2021; 29(1): 68-75
2型糖尿病患者内脏脂肪指数及其心血管疾病风险
背景:内脏脂肪指数(VAI)是一个基于简单人体测量(BMI和WC)和功能参数(甘油三酯(TG)和高密度脂蛋白胆固醇(HDL))的经验数学模型,具有性别特异性,并指示脂肪分布和功能。方法:横断面研究。该研究于2015年7月至2017年6月在BSMMU生物化学系开展。在BSMMU内分泌代谢科门诊就诊的2型糖尿病患者是我们的研究对象。认为VAI的截止值为3。结果:我们招募了105名参与者。其中男性41例,女性64例。男性和女性在身高、体重和身体质量指数方面存在显著差异。男性的身高(p =0.01)和体重(p =0.01)均高于女性。女性BMI高于男性(p =0.01)。大多数男性和女性的VAI得分高于临界值,分别为63.4%和59.4%。生化参数TG、FBG、HbA1c的平均值以VAI的截断点(d ' 3、> 3)为基础,差异有统计学意义,VAI中TG、FBG、HbA1c升高,HDL-C降低,且截断值大于3。我们发现HbA1c与FRS呈正相关(r= +)。631, p=<0.001)和VAI (r= +。结论:高内脏脂肪指数与2型糖尿病相关,心血管风险增加[j] .中华医学杂志。2021;29 (1): 68 - 75
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