A new wire patch cell for the exposure of cell cultures to electromagnetic fields at 2.45 GHz: Design and numerical characterization

A. Paffi, F. Apollonio, M. Liberti, Laura Grandinetti, S. Chicarella, G. D'Inzeo
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引用次数: 8

Abstract

Studies on the interaction between electromagnetic (EM) fields and biological systems have recently gathered further momentum due to the huge diffusion of wireless networks. In order to investigate possible effects on cultured cells of EM fields, in the frequency range typical of such a kind of communication, an in vitro exposure system has been designed and numerically characterized. The system is a Wire Patch Cell (WPC) operating at 2.45 GHz which enables the contemporary exposure of four 35 mm Petri dishes and can be inserted into a commercial incubator. Numerical dosimetry has been carried out by means of the CST Microwave Studio ® simulator. Results indicate a good efficiency, in terms of Specific Absorption Rate (SAR) in the biological sample per 1 W of input power. Moreover, the homogeneity of the SAR distribution inside each Petri dish is around 70 %, considered an acceptable value for such a kind of biological experiments.
一种用于细胞培养物暴露于2.45 GHz电磁场的新型线贴片细胞:设计和数值表征
近年来,由于无线网络的广泛普及,电磁场与生物系统之间相互作用的研究得到了进一步的发展。为了研究电磁场在这种通信的典型频率范围内对培养细胞可能产生的影响,设计了一个体外暴露系统并进行了数值表征。该系统是一个导线贴片细胞(WPC),工作频率为2.45 GHz,可以同时暴露4个35毫米的培养皿,并可以插入商业培养箱中。通过CST Microwave Studio®模拟器进行了数值剂量测定。结果表明,在生物样品的比吸收率(SAR)方面,每1 W的输入功率具有良好的效率。此外,每个培养皿内SAR分布的均匀性在70%左右,被认为是这种生物实验可以接受的值。
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