Machine Intelligence for Identification of Endothelial Corneal Layer Diseases with Novel Morphology Algorithm

K. V. Chandra, Vidya Sagar Kalapala, S. K
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Abstract

Cornea is the sensitive membrane in the eye. The transparent surface of the cornea allows visual data to process into retina. Visual imperfection is due to the functional disorder of the five layers. The vision imperfections are due to either dystrophy or degenerations. This paper focused on endothelium layer is sensitive and good transparent surface. Cell density will play a vital role for diagnosis and to improve the visibility of the objects. In-order to estimate the cell density the image acquired from the cornea is preprocessed for eliminating the noise, to detect the cells and to estimate the cell density. Coherent microscope is used to harvest the cornea images. The median filter is a adopted to curtail the unwanted high frequency components i.e. noise signal. The resulted image is much smoother for further processing. A novel morphology Method has been proposed for analyzing the filtered image for tracing the abnormality in the cell structure. The estimated results with four datasets with morphology method compared with the manually estimated results. This approach exhibits significant superior results for diagnosing the dystrophies.
基于新形态学算法的机器智能角膜内皮层疾病识别
角膜是眼睛里的敏感膜。角膜的透明表面允许视觉数据进入视网膜。视觉缺陷是由于这五层的功能紊乱。视力缺陷是由于营养不良或退化所致。内皮层是一种敏感且具有良好透明性的表面。细胞密度对诊断和提高物体的可见性起着至关重要的作用。为了估计细胞密度,对从角膜获取的图像进行预处理以消除噪声,检测细胞并估计细胞密度。用相干显微镜采集角膜图像。采用中值滤波器来抑制不需要的高频成分,即噪声信号。生成的图像更加平滑,便于进一步处理。提出了一种新的形态学方法来分析滤波后的图像,以跟踪细胞结构的异常。用形态学方法对四种数据集的估计结果与人工估计结果进行了比较。这种方法在诊断营养不良方面表现出显著的优越性。
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