ICU Clinician Perspectives on Machine Learning and the Implementation of a Mechanical Ventilation Prediction Tool: A Single Center Survey Study

E. Mlodzinski, G. Wardi, S. Nemati, L. C. Crotty Alexander, A. Malhotra
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Abstract

Rationale Although there is considerable interest in machine learning (ML) algorithms to improve patient care, implementation of these algorithms into practice has been limited. Our team developed and validated a deep learning algorithm to predict respiratory failure requiring mechanical ventilation in patients in the intensive care unit (ICU), including those with COVID-19. To help optimize implementation of this tool, we developed and disseminated a survey assessing ICU physician perspectives on the acceptability and feasibility of this tool at our institution. Methods We distributed an 8-item survey to 99 critical care trainees and faculty at our institution via email. The survey consisted of 6 multiple choice and 2 free response questions, with an ordinal scale of 1-5 used in perception-based questions. The survey was designed in accordance with international recommendations for web-based surveys. Our survey was reviewed for completeness by a team of critical care, machine learning, and implementation science experts. Data were collected over a 2- week period in May of 2021. This survey was anonymous and exempt from IRB review. Results Fifty-three critical care physicians (53.5% of providers contacted) started the survey, and of these, 88.7% (47/53) completed the survey. Fifty-nine percent (n=31) of respondents were attendings, 36% (n=19) fellows, and 3.7% (n=2) residents. Baseline knowledge of ML was low (mean= 2.40/5), with only 7.5% (n=4) of respondents rating their knowledge as a 4 or 5. Fifteen percent (n=8) had knowingly used an ML-based tool in their clinical practice. Confidence in predicting the need for mechanical ventilation due to COVID-19 (mean=3.57/5) was slightly lower than for respiratory failure due to all other causes (mean=3.89/5). Overall willingness to utilize an ML-based algorithm was favorable (mean=3.32/5). Factors most likely to increase likelihood of utilization were “high quality evidence that it outperformed trained clinicians” (mean=4.28/5), “transparency of the data utilized” (mean= 4.13/5), and “limited workflow interruption” (mean=4.09/5). Shared concerns from participants included “alarm fatigue” and “workflow interruption.” Conclusion The results suggest that ICU physicians have had limited exposure to ML-based tools, but feel such a tool would be beneficial in the context of predicting need for mechanical ventilation in ICU patients and those with COVID-19. Evidence of the tool's efficacy and data transparency were high priorities for respondents, and there was concern over workflow interruptions. This survey provided a baseline assessment of physician acceptance of a novel ML-based tool, which will be crucial in optimizing its implementation into clinical practice at our institution.
ICU临床医生对机器学习和机械通气预测工具实施的看法:单中心调查研究
尽管人们对机器学习(ML)算法改善患者护理有相当大的兴趣,但这些算法在实践中的实施受到限制。我们的团队开发并验证了一种深度学习算法,用于预测重症监护病房(ICU)患者(包括COVID-19患者)需要机械通气的呼吸衰竭。为了帮助优化该工具的实施,我们开发并传播了一项调查,评估ICU医生对该工具在我们机构的可接受性和可行性的看法。方法采用电子邮件的方式对我院99名重症监护学员和教师进行问卷调查。调查由6道选择题和2道自由回答题组成,感知题采用1-5分的顺序量表。这项调查是根据网络调查的国际建议设计的。我们的调查由一个由重症监护、机器学习和实施科学专家组成的团队审查,以确保完整性。数据收集于2021年5月,为期两周。这项调查是匿名的,不受IRB审查。结果53名重症医师(53.5%)开始了调查,其中88.7%(47/53)完成了调查。59% (n=31)的受访者是主治医生,36% (n=19)的研究员,3.7% (n=2)的住院医生。ML的基线知识很低(平均值= 2.40/5),只有7.5% (n=4)的受访者将自己的知识评为4或5。15% (n=8)在临床实践中故意使用基于ml的工具。预测因COVID-19导致的机械通气需求的置信度(平均值=3.57/5)略低于所有其他原因导致的呼吸衰竭(平均值=3.89/5)。使用基于ml的算法的总体意愿是有利的(平均值=3.32/5)。最有可能增加使用可能性的因素是“高质量的证据表明它优于训练有素的临床医生”(平均=4.28/5),“使用数据的透明度”(平均= 4.13/5)和“有限的工作流程中断”(平均=4.09/5)。参与者的共同担忧包括“闹钟疲劳”和“工作流程中断”。结论ICU医生对基于ml的工具的接触有限,但认为该工具在预测ICU患者和COVID-19患者对机械通气的需求方面是有益的。对于受访者来说,工具的有效性和数据透明度的证据是高度优先考虑的,并且存在对工作流程中断的担忧。这项调查提供了医生接受一种新型基于ml的工具的基线评估,这对于优化其在我们机构的临床实践中的实施至关重要。
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