Temporoparietal Gliosarcoma : A Case Report with Literature Review

Abstract

Gliosarcoma (GSM) is a primary tumor of the central nervous systemcomposed of both malignant glial and sarcomatous elements. GSM isclassified as grade IV according to World Health Organization (WHO)and regarded as aggressive tumor and often requires both surgeryand radiotherapy. The incidence of GSM is between 1.8%-2.8% ofall malignant gliomas and thus represents an exceptionally rareneoplasm. Consequently, our knowledge about this entity is limited tosmall retrospective case series and case reports. Here, we describe acase of a 46-year-old male with progressive right extremity weakness,accompanied with aphasia. Imaging studies showed a tumor mass inthe left temporoparietal region. Surgery was performed and gross totalremoval was achieved. Histopathology finding established a diagnosisof GSM. The extremity weakness was improved postoperatively withina week.