Electrocardiographic simulation on personalised heart-torso structures using coupled meshfree-BEM platform

Abstract

The foremost premise for the success of noninvasive volumetric myocardial Transmembrane (TMP) imaging from Body Surface Potential (BSP) recordings is a realistic yet efficient TMP-to-BSP mapping model that balances model accuracy with reconstruction feasibility. This papers presents a novel coupled meshfree-BEM platform to this forward electrocardiographic modelling. Its numerical accuracy and convergence is quantitatively assessed against analytical solutions on a synthetic geometry. Electrocardiographic simulations of various cardiac conditions on personalised heart-torso structures are consistent with existent experimental studies. In further real data validations on three post myocardial infarction patients, simulated BSP exhibit high accuracy compared to measured BSP.