Masashi Kobayashi, E. Malagueño, J. V. Santana, E. P. Perez, A. Yano
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引用次数: 3
Abstract
We conducted a survey of the prevalence of Toxoplasma gondii infection in children living in Jaboatao dos Guararapes, Pernambuco, Brazil from 1998 to 1999. This city is situated adjacent to Recife, capital of the state of Pernambuco. We determined the prevalence of specific anti-T. gondii IgG antibodies in 196 individuals from 2 to 16 years of age. Individuals who were IgG antibody negative also underwent specific anti-T. gondii IgM testing to detect recent infection with the parasite. Seroprevalence was 79.1%, and high titers of IgG antibody were observed in 49% of positive subjects. The prevalens of antibodies to T. gondii increased with age, with a multiple correlation coefficient (R) of 0.709; however, there was no significant difference in antibody status by sex. Out of 47 children who did not have specific anti-T. gondii IgG antibody, 4 were determined by specific anti-T. gondii IgM antibody analysis to have been recently infected. Stool was examined for soil-transmitted helminth eggs to assess the frequency of soil contact in the entire study population. Stool examination in the population revealed that soil-transmitted helminthiases was highly endemic, with an infection rate of 85.2%in this area. These results suggest that the primary mode of T. gondii transmission to humans is through contact with soil.
我们对1998 - 1999年巴西伯南布哥省Jaboatao dos Guararapes地区儿童弓形虫感染情况进行了调查。这座城市毗邻伯南布哥州首府累西腓。我们测定了特异性抗t抗体的患病率。在196名2至16岁的个体中检测到弓形虫IgG抗体。IgG抗体阴性的个体也进行了特异性抗t治疗。弓形虫IgM检测,以发现最近的寄生虫感染。血清阳性率为79.1%,阳性人群中IgG抗体高滴度占49%。弓形虫抗体阳性率随年龄增长而增加,多重相关系数(R)为0.709;然而,抗体状态在性别上没有显著差异。在47名没有特异性抗t抗体的儿童中。弓形虫IgG抗体,特异性抗t检测4例。弓形虫IgM抗体分析为近期感染。检查粪便中是否有土壤传播的蠕虫卵,以评估整个研究人群与土壤接触的频率。人群粪便检查显示,该地区土壤传播蠕虫病高度流行,感染率为85.2%。这些结果表明,弓形虫传播给人类的主要方式是通过与土壤接触。