Pharmacological properties of endemic plants growing in the steppes of Kazakhstan

L. K. Baktybayeva, E. R. Namaz, K. M. Kalzhan, Berlin Kennet Darrell, L. B Umbetiyarova
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Abstract

The number of people who suffer from secondary immunodeficiency diseases is increasing. Secondary immunodeficiency diseases develop due to environmental degradation, abuse of various preservatives, stabilizers in foods and long-term storage products, abuse of the use of drugs with a cytostaticeffect, the use of antibiotics in the cultivation of cattle and poultry. The compoundswere obtained fromplants of the Halostachys caspica (Pall) C.A.Mey.ex Schrenk,Suaeda microphylla Pall., Climacoptera obtusifolia (Schrenk) Botsch.Plant extracts were investigatedon myelostimulating activity. The compoundobtained from plants of the Halostachys caspica (Pall) C.A.Mey.ex Schrenk by means of water-alcoholextractionwithout heating showed high myelostimulating activity. It effectively stimulated erythro-,thrombocyto- and leukopoiesis, and in stimulating the leukocyte population, it equally effectively increased the values of granulocyte and agranulocyte leukocytes. The compounds derived from the Suaedamicrophylla Pall. and Climacoptera obtusifolia (Schrenk) Botsch.showed low myelostimulating activity.It should be noted that the water-alcohol extracts of plants without heating showed higher activity thanthe extracts that have undergone thermal heating.Key words: myelostimulating activity, endemic plants, steppes of Kazakhstan.
哈萨克斯坦草原特有植物的药理特性
患有继发性免疫缺陷疾病的人数正在增加。继发性免疫缺陷疾病的发生是由于环境退化、在食品和长期储存产品中滥用各种防腐剂、稳定剂、滥用具有细胞抑制作用的药物、在养牛和家禽中使用抗生素。这些化合物均从Halostachys caspica (Pall) C.A.Mey.ex Schrenk,Suaeda microphylla Pall等植物中分离得到。;;;;;;研究了植物提取物的骨髓刺激活性。用水-醇不加热提取法从Halostachys caspica (Pall) C.A.Mey.ex Schrenk植物中提取的化合物显示出较高的骨髓刺激活性。它有效地刺激了红细胞、血小板和白细胞的生成,在刺激白细胞群的同时,它同样有效地增加了粒细胞和粒细胞白细胞的值。这些化合物是从甜毛藻中提取的。和长翅蛾(Schrenk) Botsch。表现出低的骨髓刺激活性。值得注意的是,未经加热的植物水醇提取物的活性高于经过加热的提取物。关键词:骨髓刺激活性;特有植物;哈萨克斯坦草原。
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