MRI-based diagnostic system for early detection of prostate cancer

Abstract

MR image-based modalities, such as T2-weighted MR, Diffusion-weighted (DWI), and dynamic contrast-enhanced imaging (DCE-MRI) have been widely employed for early detection of prostate cancer in vivo. In this paper, we evaluate the diagnostic ability of diffusion weighted imaging (DWI) and dynamic contrast-enhanced imaging (DCE-MRI) for the detection of prostate cancer at early stage. This study included 28 patients (17 malignant and 11 benign) with biopsy proven prostate cancer. The diagnostic performance was calculated for DCE-MRI and DWI. Both DWI and DCE-MRI demonstrate 100% classification accuracy. These preliminary diagnostic results show the promise of using DWI as a supplement of DCE-MRI for early diagnosis of prostate cancer.