A Study on Seroprevalence of Hepatitis A Virus among Healthcare Workers at a University-Affiliated Hospital in Deajeon, Korea

The Korean Journal of Healthcare-Associated Infection Control and Prevention Pub Date : 2020-06-30 DOI:10.14192/kjicp.2020.25.1.54

Seul Ki Ji, S. Jang, Min Hee Park, J. E. Lee, Hye-Sook Jeong, Joonhong Park, S. Han, Yunmi Yi, S. Park

{"title":"A Study on Seroprevalence of Hepatitis A Virus among Healthcare Workers at a University-Affiliated Hospital in Deajeon, Korea","authors":"Seul Ki Ji, S. Jang, Min Hee Park, J. E. Lee, Hye-Sook Jeong, Joonhong Park, S. Han, Yunmi Yi, S. Park","doi":"10.14192/kjicp.2020.25.1.54","DOIUrl":null,"url":null,"abstract":"Background: In 2019, there was an outbreak of hepatitis A virus (HAV) infections in Korea. This study was performed to determine the seroprevalence of HAV among healthcare workers (HCWs) in a university-affiliated hospital and to establish an appropriate vaccination strategy against HAV for HCWs. Methods: Total antibody titers to HAV were measured using an electrochemiluminescence immunoassay kit in 1,466 HCWs. The seroprevalence of HAV and HAV vaccination rates in HCWs who were negative for anti-HAV were determined and compared among age and occupational groups. Results: In the whole study population, the seroprevalence of HAV was 49.9%. The seroprevalence was 56.3% in HCWs aged 20-24 years, decreased to 20.9% in those aged 35-39 years, and increased to 100% in those aged 60 years or more. Among HCWs who were seronegative for HAV, 70.6% received HAV vaccination. Among the occupational groups, the vaccination rate was the highest in the nurse group (80.6%) and the lowest in the doctor group (40.2%) ( P <0.001). Conclusion: HCWs in their thirties and forties, who demonstrated the lowest seroprevalence of HAV among the age groups, should be prioritized for HAV vaccination. In addition to sero-logic tests for HAV, interventions to increase vaccination rates should be applied for HCWs, particularly doctors.","PeriodicalId":107151,"journal":{"name":"The Korean Journal of Healthcare-Associated Infection Control and Prevention","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Korean Journal of Healthcare-Associated Infection Control and Prevention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14192/kjicp.2020.25.1.54","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 2

Abstract

Background: In 2019, there was an outbreak of hepatitis A virus (HAV) infections in Korea. This study was performed to determine the seroprevalence of HAV among healthcare workers (HCWs) in a university-affiliated hospital and to establish an appropriate vaccination strategy against HAV for HCWs. Methods: Total antibody titers to HAV were measured using an electrochemiluminescence immunoassay kit in 1,466 HCWs. The seroprevalence of HAV and HAV vaccination rates in HCWs who were negative for anti-HAV were determined and compared among age and occupational groups. Results: In the whole study population, the seroprevalence of HAV was 49.9%. The seroprevalence was 56.3% in HCWs aged 20-24 years, decreased to 20.9% in those aged 35-39 years, and increased to 100% in those aged 60 years or more. Among HCWs who were seronegative for HAV, 70.6% received HAV vaccination. Among the occupational groups, the vaccination rate was the highest in the nurse group (80.6%) and the lowest in the doctor group (40.2%) ( P <0.001). Conclusion: HCWs in their thirties and forties, who demonstrated the lowest seroprevalence of HAV among the age groups, should be prioritized for HAV vaccination. In addition to sero-logic tests for HAV, interventions to increase vaccination rates should be applied for HCWs, particularly doctors.

查看原文本刊更多论文

韩国大田某大学附属医院医护人员甲型肝炎病毒血清阳性率的研究

背景:2019年，韩国爆发了甲型肝炎病毒(HAV)感染。本研究旨在确定某大学附属医院卫生保健工作者(HCWs)的甲肝血清患病率，并为HCWs建立适当的甲肝疫苗接种策略。方法:采用电化学发光免疫测定试剂盒检测1466例HCWs患者的HAV总抗体滴度。测定抗甲肝病毒阴性的卫生保健工作者甲肝病毒的血清阳性率和甲肝疫苗接种率，并比较不同年龄和职业群体间的差异。结果:在整个研究人群中，HAV的血清阳性率为49.9%。20 ~ 24岁人群血清阳性率为56.3%，35 ~ 39岁人群血清阳性率下降至20.9%，60岁以上人群血清阳性率上升至100%。甲肝病毒血清检测呈阴性的卫生保健工作者中，接种甲肝疫苗的占70.6%。职业人群中，护士组接种率最高(80.6%)，医生组接种率最低(40.2%)(P <0.001)。结论:HAV血清阳性率最低的30 - 40岁年龄组应优先接种HAV疫苗。除了对甲肝病毒进行血清学检测外，还应对卫生保健工作者，特别是医生实施提高疫苗接种率的干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

The Korean Journal of Healthcare-Associated Infection Control and Prevention

自引率

0.00%

发文量