The Prevalence of Prediabetes in Sudanese Patients attending Khartoum North Teaching Hospital Referred Clinics Sudan

Abstract

Background: Prediabetes is an important health issue which rarely draw health attention, and hence it is underestimated and under diagnosed. It is importance comes from the fact that it carries the same risk as Type 2 diabetes mellitus (T2DM) and the high potential risk to develop T2DM. Objectives: To determine the prevalence of prediabetes, impaired glucose tolerance (IGT) and the risk factors that increase acquisition of T2DM in Khartoum North Teaching Hospital-Khartoum-Sudan Material and Methods: It were descriptive cross-sectional hospital-based study carried out at Khartoum North Teaching Hospital-Khartoum-Sudan during the period September 2016 to April 2017. Four hundred participants above 40 years of age were incorporated. Data was collected by structure questionnaire. Fasting blood glucose and two hours postprandial was obtained by a finger puncture under aseptic conditions. World Health Organization criteria were adopted for the diagnosis of DM (fasting plasma glucose $7.8mmol L21 or plasma glucose of $11.1mmol L21, 2h after an oral anhydrous glucose load of 75g) and IGT (fasting plasma glucose ,7.8mmol L21 and plasma glucose between 7.8mmol L21 and 11.1mmol L21, 2 h after an oral glucose load of 75g). Ethical clearance and approval for conducting this research was obtained from the State Ministry of Health and the hospital and informed verbal consent was obtained from every respondent who agreed to participate in the study. Results: During the study period; a total of 400 volunteers above 40 years were recruited. Among which the males were 195 (48.8%) and the females were 205 (51.2%). All the participants were investigated by fasting blood glucose and two hours postprandial. Hba1c was request for 27 patients (6.8%) who showed impaired glucose for both fasting and two hours. The prevalence of prediabetes was 27 (6.75%), 24 (6.00%) has impaired GT, and 0.75% has IFG. Fasting blood glucose was found to be impaired in two patients whose age 51-60 year and in only one who was more than 60year, which is significant (p value= 0.01). Conclusion: Almost among