Adopting Molecular Testing for Solid Tumors in Latin America: Challenges and Opportunities

L. Araújo, F. Costa, R. Parra, F. Pitoia, M. Rico-Restrepo, Marcos Santos, Luiz Eduardo Pino
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引用次数: 2

Abstract

Introduction: The advent of precision medicine, including molecular testing (MT), has revolutionized the cancer care landscape and may provide a path forward in the sustainability of cancer care. Methods: Americas Health Foundation (AHF) identified a panel of seven experts in MT with backgrounds in clinical oncology, molecular pathology, and bioethics from Argentina, Brazil, and Colombia. They convened for a three-day virtual meeting on November 10-12, 2021, to discuss the need for widespread access and adoption of MT for solid tumors in Latin America (LA). Results: The authors identified challenges in MT access in molecular medicine (MM) in LA and proposed suggestions to manage them. Development and implementation of human talent, infrastructure, and policy strategies are essential to provide MT in LA. This review outlines the substantial challenges faced by countries in LA to the widespread adoption of MT in oncology and provides recommendations on overcoming them. Conclusions: Despite the many advantages of MT for solid tumors, the challenges for implementation in LA healthcare systems are sizable and multidimensional. These include regional deficiencies in trained teams, fragmented healthcare systems, and inefficiently distributed budget allocations.
拉丁美洲实体肿瘤分子检测:挑战与机遇
包括分子检测(MT)在内的精密医学的出现,已经彻底改变了癌症治疗的格局,并可能为癌症治疗的可持续性提供一条前进的道路。方法:美洲健康基金会(AHF)确定了一个由来自阿根廷、巴西和哥伦比亚的七名具有临床肿瘤学、分子病理学和生物伦理学背景的MT专家组成的小组。他们于2021年11月10日至12日召开了为期三天的虚拟会议,讨论了在拉丁美洲(LA)广泛获取和采用MT治疗实体肿瘤的必要性。结果:作者明确了洛杉矶分子医学(MM)中MT获取面临的挑战,并提出了管理这些挑战的建议。人才、基础设施和政策战略的开发和实施对于在洛杉矶提供MT至关重要。本综述概述了洛杉矶国家在肿瘤学中广泛采用MT所面临的重大挑战,并提供了克服这些挑战的建议。结论:尽管MT治疗实体瘤有许多优势,但在洛杉矶医疗保健系统中实施MT的挑战是相当大的和多方面的。这些问题包括缺乏训练有素的团队、分散的医疗保健系统以及预算分配效率低下。
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