EHG Signal Analysis for Prediction of Term and Preterm using Variational Mode Decomposition and Artificial Neural Networks

Muhammad Umar Khan, Sumair Aziz, Khushbakht Iqtidar, Raul Fernandez Rojas
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Abstract

Preterm deliveries are an important cause of mortality and morbidity in newborns. Accurate and early prediction of a premature delivery can prove helpful in providing proper medication and treatment. Recording of electrical activity known as Electrohysterogram (EHG) from the abdominal surface of pregnant women corresponds to the uterus contractions. A new direction is open using EHG signals for the diagnosis of preterm births. In this research, we present a new method for the accurate classification of preterm and term EHG signals. The proposed method first filters a three-channel EHG signal using bandpass filters. Next, we combined the filtered three-channel EHG into one signal using an accumulation operation. The accumulated EHG signal was post-processed through variational mode decomposition (VMD). VMD algorithm splits the input signal into finite modes using center frequencies known as intrinsic mode functions (IMFs). An energy-based intelligent signal reconstruction approach is designed to combine IMFs having an energy level above the computed threshold. Next, the reconstructed EHG signals were split into continuous windows, and time, frequency, and Hjorth features were extracted. These features were fused to construct a distinct feature representation and were reduced using the ReliefF algorithm. We trained an artificial neural network (ANN) to obtain 98.8 % average accuracy using 10-fold cross-validation.
用变分模态分解和人工神经网络分析足月和早产的EHG信号
早产是新生儿死亡和发病的一个重要原因。准确和早期的早产预测有助于提供适当的药物和治疗。从孕妇腹部表面记录的电活动被称为子宫电图(EHG),与子宫收缩相对应。利用脑电图信号诊断早产是一个新的方向。在这项研究中,我们提出了一种新的方法来准确分类早产儿和足月脑电图信号。该方法首先使用带通滤波器对三通道EHG信号进行滤波。接下来,我们使用累加操作将滤波后的三通道EHG合并为一个信号。对累积的eeg信号进行变分模态分解(VMD)后处理。VMD算法使用称为内禀模态函数(IMFs)的中心频率将输入信号分成有限模态。设计了一种基于能量的智能信号重建方法来组合具有高于计算阈值的能级的imf。然后,将重构的EHG信号分割成连续的窗口,提取时间、频率和Hjorth特征;这些特征被融合成一个独特的特征表示,并使用ReliefF算法进行约简。我们训练了一个人工神经网络(ANN),使用10倍交叉验证获得98.8%的平均准确率。
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