The coagulative system in haemodialyzed patients: the relationship between the elderly and hypertrygliceridaemia.

V Savica, G Bellinghieri, C M Barbera, M Egitto, F Consolo
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引用次数: 0

Abstract

The coagulative system has an important role on haemodialysis and on atherosclerosis genesis; in particular the platelets are key elements of the coagulation and of atherosclerosis phenomena. Alterations of the coagulative system and increase risk of developing atherosclerosis are reported in the aging. We in this paper, report the results obtained studying the influence of the interaction between the elderly and dyslipidemia on the coagulative system in haemodialyzed patients. The obtained data showed that the hypertriglyceridaemia in interaction with the elderly accelerates and increases platelet aggregation after stimulation by ADP, Epinephrine and Collagen. So, it is important to consider hypertriglyceridaemia and age as thrombogenic factors and atherosclerosis accelerating factors in haemodialyzed patients.

血液透析患者的凝血系统:老年人与高糖苷血症的关系。
凝血系统在血液透析和动脉粥样硬化发生中起重要作用;特别是血小板是凝血和动脉粥样硬化现象的关键因素。据报道,随着年龄的增长,凝血系统的改变和动脉粥样硬化的风险增加。本文报道老年人与血脂异常相互作用对血液透析患者凝血系统影响的研究结果。所获得的数据表明,高甘油三酯血症与老年人相互作用,在ADP、肾上腺素和胶原蛋白的刺激下,加速和增加血小板聚集。因此,考虑高甘油三酯血症和年龄是血液透析患者的血栓形成因素和动脉粥样硬化加速因素是重要的。
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