Determination of pathological clonus characteristics using a haptic ankle manipulator

C. Meskers, E. de Vlugt, J. D. De Groot, W. Wisman, J. Arendzen, F. V. D. van der Helm
{"title":"Determination of pathological clonus characteristics using a haptic ankle manipulator","authors":"C. Meskers, E. de Vlugt, J. D. De Groot, W. Wisman, J. Arendzen, F. V. D. van der Helm","doi":"10.1109/ICORR.2007.4428490","DOIUrl":null,"url":null,"abstract":"Clonus is a self sustained oscillatory movement of the extremities often seen after lesions of the central nervous system. There is still controversy about the origin of clonus whether it is i) an autonomous pacemaker-like oscillator, ii) a reflexive mediated feedback property or iii) a combination of both. With the use of a haptic robot we were able to initiate clonus in patients (n=7). We would conclude the underlying mechanism to be autonomous when the frequency of movement would not change with additional external damping and inertia. Results however showed distinct changes in frequency of movement, varying the peripheral conditions. Furthermore, when the clonus was suddenly stopped by a controlled increase of a huge external damper, clear bursting was observed in the triceps EMG while there was no rotation of the ankle. In conclusion, i) clonus is initiated by spinal reflexes (probably la or lb afferents), ii) also during clonus the same spinal reflexes are likely to contribute to the maintenance of ankle rotation and iii) the after bursting directs to self sustained firing of neural circuitry. These conclusions implicate the existence of a reflexive controlled oscillator. Future research will be performed using detailed model simulations to test different gains between reflexive feedback and neural oscillations, e.g. from the alpha - motorneurons.","PeriodicalId":197465,"journal":{"name":"2007 IEEE 10th International Conference on Rehabilitation Robotics","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2007-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2007 IEEE 10th International Conference on Rehabilitation Robotics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICORR.2007.4428490","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6

Abstract

Clonus is a self sustained oscillatory movement of the extremities often seen after lesions of the central nervous system. There is still controversy about the origin of clonus whether it is i) an autonomous pacemaker-like oscillator, ii) a reflexive mediated feedback property or iii) a combination of both. With the use of a haptic robot we were able to initiate clonus in patients (n=7). We would conclude the underlying mechanism to be autonomous when the frequency of movement would not change with additional external damping and inertia. Results however showed distinct changes in frequency of movement, varying the peripheral conditions. Furthermore, when the clonus was suddenly stopped by a controlled increase of a huge external damper, clear bursting was observed in the triceps EMG while there was no rotation of the ankle. In conclusion, i) clonus is initiated by spinal reflexes (probably la or lb afferents), ii) also during clonus the same spinal reflexes are likely to contribute to the maintenance of ankle rotation and iii) the after bursting directs to self sustained firing of neural circuitry. These conclusions implicate the existence of a reflexive controlled oscillator. Future research will be performed using detailed model simulations to test different gains between reflexive feedback and neural oscillations, e.g. from the alpha - motorneurons.
用触觉踝关节机械手测定病理性冠状突特征
Clonus是一种自我持续的振荡运动的四肢,常见于中枢神经系统病变后。关于clonus的起源仍然存在争议,它是i)一个自主的类似心脏起搏器的振荡器,ii)一个反射介导的反馈特性,还是iii)两者的结合。通过使用触觉机器人,我们能够在患者中启动克隆(n=7)。当运动频率不随额外的外部阻尼和惯性而改变时,我们可以得出这样的结论:潜在的机制是自主的。然而,结果显示运动频率有明显的变化,不同的周围条件。此外,当一个巨大的外部阻尼器被控制的增加突然停止时,在没有踝关节旋转的情况下,三头肌肌电图中观察到明显的爆裂。综上所述,1)阵挛是由脊柱反射引起的(可能是la或lb传入事件),2)在阵挛期间,同样的脊柱反射可能有助于维持踝关节旋转,3)破裂后神经回路的自我持续放电。这些结论暗示了自反控制振荡器的存在。未来的研究将使用详细的模型模拟来测试反射反馈和神经振荡之间的不同增益,例如来自α -运动神经元。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信