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Abstract

CAUTIONS  Given risk of overshooting recommended max increases; best to aim for a correction goal that falls well short of rates associated with harm (correction limit) and to monitor serum sodium and urine volume frequently  Serum sodium 105 mmol/L or less, hypokalemia, alcoholism, malnutrition, advanced liver disease: patients at higher risk of developing osmotic demyelination syndrome  Hypokalemia; giving potassium alone may simultaneously correct hyponatremia and hypokalemia; giving additional sodium may lead to an overly rapid sodium correction PREGNANCY/BREAST FEEDING: Contact pharmacy for most recent information