The Role of System connective tissue dysplasia in the Formation of hernia Inguinal Area

R. Railianu, A. Botezatu, G. I. Podoliniy, Y. Paskalov
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Abstract

Relevance. Despite advances in the treatment of inguinal hernias are still being discussed, the issues of post-operative wound complications and disease recurrence. The inclusion in the list of risk factors for complicated postoperative course of systemic connective tissue dysplasia will allow a new look at the mechanisms of herniation in the groin area and develop morphologically adapted methods of surgical treatment. Objective. Study the characteristics of connective tissue dysmorphogenesis at hernia protrusions in the inguinal region. Results. In the main group absolutely reliable connection with all possible variants of hernia disease in the inguinal region possessed 6 (12 %) the morphological predictors, namely: dystonia dysfunction, curvature of the spine, hallus valgus, hypermobility joints, varicose disease of the lower limb and hemorrhoids. The curvature of a backbone and hyper mobility of joints occurred among manifestations of a dismorfizm at patients of control group. The area of electromyograms at reduction of muscles forming the torn down hernia the inguinal interval, on 20 % inferior area electromyograms reduction of similar muscles on contralateral from inguinal hernia to the side and on 61,4 % of area electromyograms contraction of the groin muscles of the control group patients. In a smaller proportion, but with similar characteristics reduced groups of lateral muscles, which is considered by us as local functional predictors of the implementation of systemic connective dysplasia in the hernia disease of the inguinal region. The density of the collagen fibers in the dermis of patients with inguinal hernias was 75.6 + 1.9%, which is 12,3 % lower than the result of such collagen metrics index of patients of the control group. Intensity of coloring of micropreparations of dermis of patients of control group was at the level of 36,33 + 2,1, that on 1,8 times less than this index in patients of the basic group. Conclusions. Thus, results of histology confirm reliability of the revealed morphological and local functional prerequisites of formation of inguinal hernias at connective dysplasia.
系统结缔组织发育不良在腹股沟疝形成中的作用
的相关性。尽管腹股沟疝的治疗进展仍在讨论中,但术后伤口并发症和疾病复发的问题仍然存在。将系统性结缔组织发育不良纳入复杂术后过程的危险因素列表,将使人们对腹股沟区疝的机制有了新的认识,并发展出适合形态学的手术治疗方法。目标。研究腹股沟区突出疝结缔组织畸形的特点。结果。在主要组中,与腹股沟区所有可能的疝病变异有绝对可靠联系的形态学预测因子有6个(12%),即:肌张力障碍、脊柱弯曲、拇外翻、关节活动过度、下肢静脉曲张疾病和痔疮。脊柱的弯曲和关节的过度活动发生在患者的变形在对照组的表现。腹股沟间隙形成撕裂疝的肌肉收缩区肌电图,对侧从腹股沟疝到侧边的类似肌肉收缩区肌电图占比为20%,对照组腹股沟肌肉收缩区肌电图占比为65.4%。比例较小,但具有相似特征的侧肌群减少,我们认为这是腹股沟区疝疾病中全身性结缔组织发育不良的局部功能预测因素。腹股沟疝患者真皮胶原纤维密度为75.6 + 1.9%,比对照组患者该胶原指标低12.3个百分点。对照组患者的真皮微制剂着色强度为36,33 + 2,1,比基础组患者的着色强度低1,8倍。结论。因此,组织学结果证实了结缔组织发育不良腹股沟疝形成的形态学和局部功能先决条件的可靠性。
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