Der beatmete Patient mit Sepsis und Multiorgan-Dysfunktion - Rasche zielgerichtete Therapie für eine bessere Prognose

Abstract

Septic diseases continue to be conspicuous for their high prevalence on intensive-care units and for their high lethality. It is particularly effective to initiate treatment at a very early stage by, first of all, stabilizing the patient haemodynamically and by administering antibiotics without delay - which, of course, requires an early diagnosis. As the treatment proceeds, it is of particular importance to sanitize septic areas and to make the necessary arrangements for protective ventilation of the patient and for blood sugar control. General supportive or adjunctive therapy is governed by the current treatment recommendations for septic conditions, severe sepsis and septic shock. It is the aim of this therapeutic concept consisting of early on-target measures and causal procedures (for example, focal sanitation) and of the supporting adjunctive and prophylactic measures to initially prevent as far as possible any aggravation of the disease and to subsequently stabilize the multi-organ distress syndrome, as well as to protect the patient as much as possible by initiating ventilation of the lungs by means of a maximally protective and brief procedure.