Prevalence and persistence of breathing disorders in chronic heart failure patients: preliminary results from home telemonitoring in the HHH study

G. Pinna, R. Maestri, E. Gobbi, S. Capomolla, C. Campana, A. Di Lenarda, M. Emdin, D. Andrews, M. L. La Rovere, P. Johnson, A. Mortara, P. Sleight
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Abstract

In this paper we present preliminary results of the European Community multicountry trial HHH (Home or Hospital in Heart Failure), which assessed the prevalence and persistence of nocturnal breathing disorders in mild-to-moderate CHF patients. All subjects (465) carried out a baseline respiratory recording in the hospital, followed by 12 recordings (one per month) at home. The latter were totally self-managed by the patients, and data were transmitted to the referring hospital through telephone lines. We found that 43% of the patients had a periodic breathing pattern (PB, waxing and waning of ventilation with or without apneas) during the night lasting >1 hour, and the apnea-hypopnea index (AHI) was >5 events/hour in 51% of them. During the 1-year follow-up, a PB>1 hour and an AHI>5 events/hour were persistent (i.e., occurred in >50% of the recordings) in 43% and 52% of the patients. These findings confirm the high prevalence of nocturnal breathing disorders in CHF patients and show that in a large proportion of patients they tend to persist over time
慢性心力衰竭患者呼吸障碍的患病率和持续性:HHH研究中家庭远程监测的初步结果
在本文中,我们介绍了欧洲共同体多国试验HHH(心衰家庭或医院)的初步结果,该试验评估了轻中度CHF患者夜间呼吸障碍的患病率和持久性。所有受试者(465人)在医院进行了一次基线呼吸记录,随后在家中进行了12次记录(每月一次)。后者完全由患者自行管理,数据通过电话线传送到转诊医院。我们发现,43%的患者在夜间出现周期性呼吸模式(有或无呼吸暂停),持续时间>1小时,其中51%的患者呼吸暂停低通气指数(AHI) >5次/小时。在1年的随访中,43%和52%的患者持续出现PB>1小时和AHI>5事件/小时(即发生在>50%的记录中)。这些发现证实了夜间呼吸障碍在CHF患者中的高患病率,并表明在很大一部分患者中,这些疾病往往会持续一段时间
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