OSA-CCNN: Obstructive Sleep Apnea Detection Based on a Composite Deep Convolution Neural Network Model using Single-Lead ECG signal

Yu Zhou, Yinxian He, Kyungtae Kang
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Abstract

Obstructive sleep apnea (OSA) is a common sleeping issue that makes it difficult to breathe while you sleep and is linked to a number of other disorders, including cardiovascular conditions, such as hypertension and coronary heart disease. Nocturnal polysomnography (PSG) is one of the clinical diagnostic criteria for OSA, which is a painful and expensive form of diagnosis as it requires manual interpretation by experts and takes a lot of time. ECG-based techniques for diagnosing OSA have been introduced to alleviate these problems, but the most of solutions that have been put up thus far rely on feature engineering, which requires substantial specialist knowledge and expertise. In this study, we present a novel approach for classifying OSA based on a single-lead ECG signal conversion and a composite deep convolutional neural network model. The ECG signal is transformed into scalogram images with heart rate variability (HRV) characteristics and Gramian Angular Field (GAF) matrix images with temporal characteristics, incorporating the temporal properties of the ECG, to create the hybrid image dataset. The composite model contains three sub-convolutional neural networks, two of which utilize fine-tuned AlexNet and ResNet models, the third is a convolutional neural network with five residual blocks that are evaluated by a voting mechanism. The PhysioNet Apnea-ECG database was used to train and evaluate the proposed model. The results show that the proposed classifier achieved 90.93% accuracy, 83.86% sensitivity, 95.29% specificity, and 0.89 AUC on hybrid image datasets.
OSA-CCNN:基于单导联心电信号的复合深度卷积神经网络模型检测阻塞性睡眠呼吸暂停
阻塞性睡眠呼吸暂停(OSA)是一种常见的睡眠问题,它会使你在睡觉时呼吸困难,并与许多其他疾病有关,包括心血管疾病,如高血压和冠心病。夜间多导睡眠图(PSG)是OSA的临床诊断标准之一,但由于需要专家人工解读且耗时长,是一种痛苦且昂贵的诊断方式。为了缓解这些问题,已经引入了基于脑电图的OSA诊断技术,但迄今为止提出的大多数解决方案都依赖于特征工程,这需要大量的专业知识和专业知识。在这项研究中,我们提出了一种基于单导联心电信号转换和复合深度卷积神经网络模型的OSA分类新方法。将心电信号转化为具有心率变异性(HRV)特征的尺度图图像和具有时间特征的格拉曼角场(GAF)矩阵图像,结合心电信号的时间特性,生成混合图像数据集。该复合模型包含三个子卷积神经网络,其中两个使用微调的AlexNet和ResNet模型,第三个是具有五个剩余块的卷积神经网络,通过投票机制进行评估。使用PhysioNet呼吸暂停- ecg数据库对所提出的模型进行训练和评估。结果表明,该分类器在混合图像数据集上的准确率为90.93%,灵敏度为83.86%,特异性为95.29%,AUC为0.89。
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