Smoking, Periodontitis and Vascular Disease -Collaboration Study with Dentists and Vascular Surgeons

Abstract

Weak oral bacteria such as periodontal bacteria have been observed in various arterial and venous lesions with epidemiological data reported prior to the discovery of bacterial invasion into vessels. Rich lymph vessels easily bring the bacteria from the mouth to the neck and the venous angle, which is directly open to the blood vessels. Periodontal bacteria travel within platelets. Periodontal bacteria, especially P. gingivalis aggregates platelets and forms thrombus. At the same time, secretions such as serotonin, various cytokines, and adhesion factors also appear in the blood. The characteristic of the arterial lesions are dependent on the age of the patient and the condition of the endothelial cells. In young patients, infectious incidents occur due to embolic mechanisms in Buerger disease or adhesion to the superficial veins valves in varicose veins. In aged patients, incidents result in adhesion in the proximal aorta, coronary arteries or large arteries. The hypotheses here unify the evidence or vessel lesion development and explain possible discrepancy between vascular diseases. We were able to emphasize the collaboration study in this study with dentists and vascular surgeons.