Simulasi Blood Type Inheritance dengan Pemrograman Software Wolfram

Bioma : Berkala Ilmiah Biologi Pub Date : 2022-06-13 DOI:10.14710/bioma.24.1.66-72

Asep Komara Walkis Hayadri, H. P. Kusumaningrum, Anton Budiharjo

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Abstract

Bioinformatics as an interdisciplinary science, combine biology, computer science, information technology, mathematics, and statistics in order to analyze and interprete biological data. Bioinformatics has been used for in silico analysis of biological questions using mathematical and statistical techniques. In silico analysis allows indirect simulation through a series of instructions put into a device, usually a computer. Nowadays, the simulation of biological aspects, especially genetics, with in silico method has been widely applied for several fields. The ABO blood type inheritance system in humans has rules that its mechanism can be applied into the Wolfram software programming, for example showing the possibility of blood groups being inherited from blood type O pairs with AB. The latest statistical data regarding the number of Indonesians who have reported their blood type has not yet reached 25% of the total population of Indonesia. Wolfram software is expected to be an accurate and fast blood type detector to record the entire population of Indonesia. The purpose of this study was to simulate Blood Type Inheritance with Wolfram Software Programming on ABO blood type inheritance data and see the suitability of the simulation results with real blood type inheritance data. The method used to simulate blood type inheritance is a survey of 12 families for the data of blood group, the next step is to enter the data one by one into the simulation model to observe the output results then matched with real data to determine the results of ABO blood type inheritance. Simulation of blood type inheritance can be done by programming the Wolfram Mathematica software and blood type data from 12 families can be simulated through the ABO blood inheritance system on Wolfram Mathematica, with details of the simulation predicting the blood groups of 2 families, simulation of 9 families according to real data, and simulation of 1 family does not match the real data.

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模拟血型遗传邓安软件Wolfram

生物信息学是一门跨学科的科学，它结合了生物学、计算机科学、信息技术、数学和统计学来分析和解释生物数据。生物信息学已被用于使用数学和统计技术对生物学问题进行计算机分析。计算机分析允许通过输入设备(通常是计算机)的一系列指令进行间接模拟。目前，计算机模拟生物学特别是遗传学的方法已广泛应用于多个领域。人类的ABO血型遗传系统有规律，其机制可以应用到Wolfram软件编程中，例如显示了O型血与AB型血对遗传血型的可能性。最新的统计数据显示，印度尼西亚报告自己血型的人数尚未达到总人口的25%。Wolfram软件有望成为一种准确、快速的血型检测器，以记录整个印度尼西亚的人口。本研究的目的是利用Wolfram Software Programming对ABO血型遗传数据进行血型遗传模拟，并观察模拟结果与真实血型遗传数据的适用性。模拟血型遗传的方法是对12个家庭的血型数据进行调查，下一步是将这些数据逐一输入到模拟模型中，观察输出结果，然后与真实数据进行匹配，从而确定ABO血型遗传的结果。通过对Wolfram Mathematica软件进行编程，可以模拟血型遗传，通过Wolfram Mathematica上的ABO血型遗传系统可以模拟12个家族的血型数据，其中模拟预测了2个家族的血型，根据真实数据模拟了9个家族的血型，模拟1个家族的血型与真实数据不匹配。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Bioma : Berkala Ilmiah Biologi

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