SCREENING INVESTIGATIONS OF VITAMIN D CONTENT DIFFERENT POPULATION GROUPS OF BIG SOCHI

Abstract

Data on vitamin D metabolism suggest that it is a secosteroid prohormone. Current studies have shown that the mechanism of functioning of vitamin D is associated with a specific receptor of the hormonally active form of this vitamin (VDR). Receptors for vitamin D are identified in more than 40 target tissues of the body (bones, muscles, intestine, kidneys, heart, prostate gland, mammary glands, pancreas), in particular in most cells of the immune system and epithelial cells lining the mucous membranes which determines many of its biological effects. Vitamin D levels affect 172 major physiological indicators of human health [1,2]. Determining the optimal values for vitamin D connect in body plays a key role in establishment of recommendations for maintaining the normal status of this vitamin throughout the year, including winter months. In connection with the discovery of new extraskeletal (non-calcemic) functions of vitamin, as well as the influence on its content of geographical, ethnic and age factors, it became necessary to clarify the norms of physiological need for this vitamin based on regional conditions [2]. The work presented is a part of comprehensive research on optimizing the reference values of diagnostic systems and enzyme immunoassay systems, in particular, to definite human populations. The investigations presented out in this work revealed the most vulnerable groups in relation to D deficiency and revealed significant seasonal degradation of vitamin content, despite the fairly comfortable climate conditions of the coast of Greater Sochi.