Abbau von 2H-pyridazin-3-on durch ein Mycobacterium

Abstract

Bacteria growing on 2H-pyridazin-3-one as sole carbon source could be isolated from garden soil. The bacteria could be identified as a mycobacterium. The GC-content of the DNA was determined as 61,4%. Typical mycobactins could be isolated and identified. With several methods no intermediate of the degradative pathway could be detected.

Growth studies with different compounds showing structural analogy to 2H-pyridazin-3-one suggest, that the mycobacterium strain exhibits a high specificity towards this compound.